Body Weight-Based Protocols During Whole Body FDG PET/CT Significantly Reduces Radiation Dose without Compromising Image Quality:Findings in a Large Cohort Study

Academic Radiology
Charbel SaadeKarl Asmar

Abstract

To investigate radiation dose reduction during whole body fluorodeoxyglucose (18F-FDG) positron emission tomographic (PET)/computed tomography (CT) by employing weight-based protocols. One thousand and twenty-eight patients were referred for 18F-FDG PET/CT study with one of two protocols: conventional protocol I; 120 kVp, 120 mAs, 0.5 second rotation time, pitch 0.8 mm/rot across all body weights; four-tier body weight protocol II all used 140 kVp, 0.75 seconds rotation time and pitch 0.8 mm/rot: Protocol A (≤60 kg): 35 mAs, Protocol B (61-80 kg): 50 mAs, Protocol C (81-100 kg): 65 mAs, and Protocol D: (>101 kg): 100 mAs. All protocols employed tube current modulation. Quantitative and qualitative image visual grading characteristics assessed image quality. Patient demographics demonstrated no significant difference between each protocol except for patient weight in weight protocol IIB (p < 0.009). Mean effective dose in all protocols were significantly lower in Protocol B compared to A (p < 0.009). Contrast-to-noise ratio demonstrated no differences between each protocol (p < 0.21) except for weight protocol in protocol IIA (<60 kg, p = 0.035) with the visual grading characteristics demonstrating preference over protocol II co...Continue Reading

Citations

Mar 18, 2020·EJNMMI Physics·V BertoliniS Cola
Aug 14, 2021·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Nazreen WaelehFathinul Fikri Ahmad Saad

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