Body weight: estimation of risk for breast and endometrial cancers

The American Journal of Clinical Nutrition
R Ballard-Barbash, C A Swanson

Abstract

Consistent, positive, and independent associations between body weight or body mass index (BMI), weight gain, and various measures of central adiposity and the incidence of endometrial cancer exist. Increases in relative risks of 2-3.5 are reported for women with BMIs (in kg/m2) > or = 28-30, for women in the fourth compared with the first quartile of measures of central adiposity, and for women with weight gains from young adulthood to middle age of > or = 27 kg. Furthermore, endometrial cancer mortality is increased in heavier and taller women. Associations between breast cancer incidence and these measures of adiposity vary by age and menopausal status at the time of diagnosis. Heavier women appear to be at decreased risk for developing premenopausal breast cancer; relative risks of approximately 0.6 were reported for women with BMIs > or = 26-27. Conversely, heavier women are at increased risk of developing and dying from postmenopausal breast cancer. Although contradictory findings have been observed in cohort studies, modest increases in relative risks on the order of 1.2-1.5 were reported in older postmenopausal women with BMIs of > or = 28-30. Furthermore, adult weight gain and increased central adiposity have been cons...Continue Reading

Citations

Dec 2, 2005·Breast Cancer Research and Treatment·Stephanie A Navarro SilveraThomas E Rohan
Mar 17, 2004·The Breast : Official Journal of the European Society of Mastology·A R Carmichael, T Bates
Jun 29, 2004·Psychoneuroendocrinology·Heather C AbercrombieDavid Spiegel
Dec 16, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·S ColdC Rose
Sep 8, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·C M FriedenreichK S Courneya
Nov 1, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M D DaneseR I Griffiths
Sep 20, 2005·Breast Cancer Research : BCR·Reza HakkakSoheila Korourian
Mar 31, 1998·Environmental Health Perspectives·L T FrameJ E Leakey
Oct 8, 1999·American Journal of Public Health·G OsterG A Colditz
Sep 10, 2002·The Lancet Oncology·France BianchiniHarri Vainio
Sep 11, 2012·Journal of Community Health·Eden R CardozoErica E Marsh
May 17, 2011·Gastrointestinal Endoscopy Clinics of North America·Dan E Azagury, David B Lautz
Jun 24, 2010·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Alessandra BittoFrancesco Squadrito
Aug 11, 2011·The Journal of Obstetrics and Gynaecology Research·Dong Hoon SuhSoon-Beom Kang
May 26, 2012·American Journal of Industrial Medicine·Yeon-Soon AhnKyoo-Sang Kim
Apr 27, 2011·The Journal of Obstetrics and Gynaecology Research·Chang-Ching YehKuan-Chong Chao
Sep 18, 2012·American Journal of Obstetrics and Gynecology·Eden R CardozoErica E Marsh
Feb 2, 2010·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Karen PendergastJean-Pierre Despres
Apr 17, 1998·Obesity Research·A M Wolf, G A Colditz
Feb 27, 1999·Preventive Medicine·R M MerrillE J Feuer
Oct 19, 2001·Gynecologic Oncology·L R DuskaA F Fuller
Dec 9, 2008·Gynecologic Oncology·Kellie S MatthewsRodney P Rocconi
Oct 1, 2004·Nutrition and Cancer·Kathy L RadimerGreta Lee Splansky
Jan 20, 2000·Journal of the National Cancer Institute·J VerloopF E van Leeuwen
Feb 5, 1998·Journal of the National Cancer Institute·M D GammonJ A Britton
Jul 31, 2004·Emergency Medicine Australasia : EMA·Peter Grant, Mark Newcombe
Aug 3, 2004·Nature Reviews. Cancer·Eugenia E Calle, Rudolf Kaaks
Aug 24, 2004·Oncogene·Eugenia E Calle, Michael J Thun
Jun 17, 2014·Journal of Korean Medical Science·Hyo Sook BaeYong Min Kim
May 10, 2006·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·A PapadiaE M Salom
Oct 14, 2006·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·A R Carmichael
Nov 13, 2002·European Journal of Clinical Nutrition·L S AugustinC La Vecchia
Mar 26, 2008·British Journal of Cancer·K LindemannA Eskild
Sep 24, 2005·The Journal of Obstetrics and Gynaecology Research·Wataru YamagamiShiro Nozawa
Jul 27, 2006·British Journal of Cancer·J J GoedertUNKNOWN HIV/AIDS Cancer Match Study
May 1, 2008·Expert Opinion on Medical Diagnostics·Faina LinkovAnna Lokshin
Feb 26, 2004·Obesity Research·K-L Catherine JenWilliam M Hryniuk
Nov 1, 2007·Women's Health·Johannes C HuberClemens B Tempfer
Aug 23, 2017·Journal of Cancer Research and Clinical Oncology·Andrea PapadiaMichael D Mueller
Feb 22, 2002·International Journal of Cancer. Journal International Du Cancer·Yadong CuiTrudy L Bush

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Anesthesia
Ayumi FujinagaShuichi Nosaka
Primary Care
David G Weismiller
Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
A ManciniF Crucitti
© 2021 Meta ULC. All rights reserved