Body weight recovery, eating difficulties and compliance with dietary advice in the first year after stem cell transplantation: a prospective study

Bone Marrow Transplantation
J A IestraD Kromhout

Abstract

Among healthcare professionals there is no consensus about the best policy to increase oral intake and promote recovery in the post-hospital phase after bone marrow or blood stem cell transplantation. In order to evaluate body weight recovery and compliance with dietary advice among these patients, we performed a prospective longitudinal study in the first year post transplant. At five time intervals (days 50, 75, 125, 200 and 350) patients received a nutritional questionnaire with items on nutrition-related symptoms, physical condition, body weight recovery and compliance with dietary advice. From the initial cohort of 135 patients 69 completed the study. Prevalence of eating difficulties was high (66% at day 50). Anorexia, dry mouth, altered taste, nausea and tiredness were the symptoms most strongly associated with eating difficulties. Compliance with dietary advice was poor. Conditioning regimen was found to be a prognostic factor for body weight status at day 350. In more than 50% of the TBI-treated patients body weight was not restored to 95% of the pretreatment value within 1 year after transplant. Future studies should focus on increasing energy and protein intake in the TBI-treated subgroup.

References

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Citations

Aug 10, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Jane B HopkinsonJulia M Addington-Hall
Jan 12, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Yun-Chi HungElisabeth Isenring
Jan 20, 2009·Bone Marrow Transplantation·H M ChungT J Smith
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Oct 12, 2004·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·Cheryl Rodgers
Jul 24, 2008·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·Cheryl Rodgers, Teresa Walsh
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May 23, 2019·Einstein·Sandra Elisa Adami Batista GonçalvesAndrea Z Pereira
Jun 27, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Mariana Henriques FerreiraLuciana Corrêa
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Mar 31, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Joel B EpsteinGregory Smutzer

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