Bohlmann-Rahtz cyclodehydration of aminodienones to pyridines using N-iodosuccinimide.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Mark C Bagley, Christian Glover

Abstract

Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N-iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total regiocontrol.

References

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Citations

Sep 26, 2013·The Journal of Organic Chemistry·Dharmit MistryMichael I Page
Feb 14, 2019·Organic & Biomolecular Chemistry·Yilmaz Kelgokmen, Metin Zora

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Methods Mentioned

BETA
column chromatography

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