Bonding capacity in bone of HIP-processed HA-coated titanium: mechanical and histological investigations

Journal of Biomedical Materials Research
H WieH R Haanaes

Abstract

The main problems using plasma-sprayed hydroxyapatite (HA) as a coating material on metallic implants are its porosity, low fatigue strength, and weak adherence to the metallic substrate. To overcome these problems a new technique using hot isostatic pressing (HIP) has been developed for producing HA-coated titanium (Ti) implants. Specimens produced at a maximum temperature of 850 degrees C and a maximum pressure of 720 bar displayed a dense, glassy, 25-microns thick coating with small amounts of porosity and a mean surface roughness of 0.7 microns, as compared with 1.6 microns for sandblasted Ti. Twenty conical HA-coated (720 and 100 bar pressure) and 10 noncoated Ti implants were inserted through the cortex of the lower margin of the mandibles of sheep and allowed to heal for 60 days. Push-out tests for implants processed at 720 bar pressure showed substantially higher bone/implant bonding values than for sandblasted Ti implants. Histological studies indicated a direct contact and probably chemical bonding between bone tissue and the HA coatings. The area of contact was almost 3 times as large as for the Ti implants. The adherence of the 100-bar coating to the Ti surface was inferior to the 720-bar coating, as shown by the lo...Continue Reading

References

Aug 1, 1992·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·E M PinholtG Bang
Sep 1, 1989·Journal of Biomedical Materials Research·J K LawA B Weiss
Nov 1, 1989·Journal of Biomedical Materials Research·J Black
Jan 1, 1988·Annals of the New York Academy of Sciences·W R Lacefield
Dec 1, 1987·Journal of Biomedical Materials Research·K de GrootP Serekian
Mar 1, 1985·Biomaterials·T AlbrektssonB Ivarsson
Jun 1, 1983·The Journal of Prosthetic Dentistry·B Kasemo

❮ Previous
Next ❯

Citations

Jul 9, 1999·Journal of Biomedical Materials Research·J A ParrW E Roberts
Jul 3, 2010·Tissue Engineering. Part a·Jennifer Z PaxtonKeith Baar
Dec 17, 2008·Revue de chirurgie orthopédique et réparatrice de l'appareil moteur·J GirardH Migaud

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.