Bone-bonding behavior of titanium alloy evaluated mechanically with detaching failure load

Journal of Biomedical Materials Research
K TakatsukaT Kokubo

Abstract

Although titanium (Ti) and Ti alloy are generally classified as bioinert materials in terms of their bonding to bone tissue, it is still unclear whether they bond chemically to bone. In this study, we examined the bone-bonding ability of Ti alloy (Ti-6Al-4V) using smooth-surfaced plates under non-load-bearing conditions. The bone-bonding behavior was evaluated mechanically by means of the detaching test reflecting tensile force. After implantation of the plates into the tibiae of rabbits for 4, 8, 16, and 25 weeks, detaching tests were performed. The failure load of the Ti alloy plates was close to 0 kg at 4 and 8 weeks, but gradually increased with time, reaching 0.334 kg at 16 weeks and 2.852 kg at 25 weeks on average. Histologic examination by Giemsa surface staining and SEM showed no differences between specimens at 8, 16, and 25 weeks, when Ti alloy plate made direct content with bone without any fibrous tissue. By SEM-EPMA, no clear calcium-phosphorus (Ca-P)-rich layer at the interface between the Ti alloy and bone tissue was evident, although a thin bone tissue was observed on the detached Ti alloy plate. The present results indicate that from both mechanical and histologic viewpoints, Ti alloy bonds directly to bone und...Continue Reading

References

Aug 1, 1991·Journal of Biomedical Materials Research·Y FujitaT Kokubo
Oct 1, 1991·Journal of Biomedical Materials Research·S KotaniT Kokubo
Jan 1, 1990·Calcified Tissue International·G DaculsiI Barbieux
Oct 1, 1990·Journal of Biomedical Materials Research·J E DaviesA Shiga
Jul 1, 1985·Journal of Biomedical Materials Research·T NakamuraS Itoo
Mar 1, 1988·Journal of Biomedical Materials Research·D P RiveroJ O Galante
Nov 1, 1986·Journal of Biomedical Materials Research·T KitsugiT Shibuya
Jan 1, 1969·Scandinavian Journal of Plastic and Reconstructive Surgery·P I BrånemarkA Ohlsson
Sep 1, 1983·The Journal of Prosthetic Dentistry·P I Brånemark
Feb 1, 1983·Acta Orthopaedica Scandinavica·L LinderI Lundström
May 1, 1981·Journal of Biomedical Materials Research·U GrossJ Sela
Dec 1, 1993·Journal of Biomedical Materials Research·P Li, K de Groot

❮ Previous
Next ❯

Citations

Jan 1, 1996·Journal of Biomedical Materials Research·X WangC M Agrawal
Apr 1, 1997·Journal of Biomedical Materials Research·X Wang, C M Agrawal
Jul 11, 1998·Journal of Biomedical Materials Research·P Li, P Ducheyne
Jun 10, 1998·Journal of Biomedical Materials Research·H LinK de Groot
Jan 14, 2010·Journal of Materials Science. Materials in Medicine·Wen-Fu HoShih-Ching Wu
Dec 31, 2002·Biomaterials·Davide ZaffeUgo Consolo
Jun 25, 2002·Implant Dentistry·J M ManeroJ A Planell
Apr 17, 2009·Journal of the Royal Society, Interface·Young-Taeg SulTomas Albrektsson
Nov 28, 2013·Journal of Materials Science. Materials in Medicine·Kazuhiro Imai, Sachiko Hiromoto
Feb 11, 2015·BioMed Research International·Jun-Sik KimJae-Pyeong Ahn
Aug 19, 2007·Biomaterials·John E Davies
May 15, 2004·Clinical Oral Implants Research·Maawan KhadraHans R Haanaes
Jun 8, 2011·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Ki-Won LeeKyo-Han Kim
Nov 19, 2011·Clinical Oral Implants Research·Young-Taeg SulCarina Johansson
May 25, 2012·Journal of Biomedical Materials Research. Part a·Maximilian HaenleRainer Bader
Sep 23, 2014·Journal of Biomechanics·Marco PiccininiAnselm Wiskott
Oct 27, 2016·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Brian D HoltStefanie A Sydlik
Jan 1, 1996·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·K KieswetterB D Boyan
May 1, 2016·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Alexander A WhitePatrick J Atkinson
Jan 23, 2004·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·S Szmukler-MonclerJ P Bernard
May 8, 2018·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Jue LiuJianming Ruan
Sep 17, 2004·Scandinavian Journal of Rheumatology·F B Christensen, C Bünger
Jul 8, 2003·Microscopy Research and Technique·J M ManeroJ A Planell
Feb 3, 2007·Journal of Biomedical Materials Research. Part a·A BigiR Cortivo
Aug 14, 1998·Acta Orthopaedica Scandinavica·R Skripitz, P Aspenberg
Nov 14, 1997·Journal of Biomedical Materials Research·W Q YanT Kokubo
Aug 5, 2017·Materials·Kazuhiro Imai, Sachiko Hiromoto
May 11, 2018·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Alessandro BistolfiAlessandro Massè

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved