Bone density and heel ultrasound testing do not identify patients with dialysis-dependent renal failure who have had fractures

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Sophie A JamalGillian A Hawker

Abstract

Patients with dialysis-dependent renal failure are at increased risk for low-trauma fractures. However, the optimal means of identifying patients at high risk for fracture is not known. We assessed the association between fracture history and two tests of bone mineral density (dual x-ray absorptiometry [DEXA] and calcaneal ultrasound) among patients with hemodialysis-dependent renal failure. We evaluated 71 men and 33 women aged 55 years or older who had been receiving hemodialysis for at least 1 year. All patients underwent spinal radiography, DEXA of the hip and lumbar spine, and calcaneal ultrasonography. We assessed risk factors for low-trauma fractures by questionnaire and medical chart review. Of patients, 52% had a fracture on spinal radiographs or a history of a low-trauma fracture, 69% had osteopenia by DEXA, and 26% had a low heel ultrasound measurement. Neither DEXA nor calcaneal ultrasound was associated with fracture history, however. Our findings indicate that fractures among patients with dialysis-dependent renal failure are common. Tests of bone strength do not adequately identify patients with a history of fractures. Prospective studies to determine the optimal method of identifying patients with dialysis-depen...Continue Reading

References

Aug 3, 1989·The New England Journal of Medicine·H H Malluche, M C Faugere
Nov 1, 1994·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J A Kanis
Mar 1, 1995·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·D C BauerK Stone
Mar 1, 1994·Journal of the American Society of Nephrology : JASN·H H Malluche, M C Monier-Faugere
Jan 1, 1993·American Journal of Nephrology·C GabayR Rizzoli
Oct 1, 1996·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M S SteinG J Becker
Jan 1, 1997·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C F NjehC M Langton
Jun 30, 1998·Journal of the American Society of Nephrology : JASN·H C SchoberA M Parfitt
Aug 26, 1998·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·A M Parfitt
Jan 20, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·D M BlackS R Cummings
Feb 19, 1999·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·K AtsumiT Inoue
Apr 21, 1999·The American Journal of the Medical Sciences·K Sakhaee, G B Gonzalez
May 11, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·L A RubinD E Cole
Aug 26, 1999·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·M W TaalT Masud
Aug 26, 1999·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·M W TaalM J Cassidy
Jan 5, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S A JamalG A Hawker
Jul 8, 2000·Kidney International·A M AlemC Stehman-Breen
Nov 30, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M Coco, H Rush
Jul 14, 2001·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·B AbrahamsenS P Nielsen
Jan 25, 2006·The Journal of Craniofacial Surgery·Wilberto Cortes, Arun K Gosain
May 26, 2011·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Hartmut H MallucheMarie-Claude Monier-Faugere

❮ Previous
Next ❯

Citations

Apr 17, 2010·Journal of the American Society of Nephrology : JASN·Thomas L NickolasElizabeth Shane
Oct 24, 2008·Clinical Journal of the American Society of Nephrology : CJASN·Nigel D ToussaintPeter G Kerr
Apr 21, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Robert H YenchekUNKNOWN Health, Aging, and Body Composition Study
Apr 1, 2012·International Journal of Endocrinology and Metabolism·Osamu SaitoEiji Kusano
Oct 12, 2013·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S A JamalT L Nickolas
Jun 11, 2010·Journal of Endocrinological Investigation·M FusaroG Guglielmi
Aug 5, 2008·Néphrologie & thérapeutique·Justine BacchettaDenis Fouque
Feb 5, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Mary B Leonard
Jul 12, 2007·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Mary B Leonard
Jun 27, 2006·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S A JamalD C Bauer
Jun 26, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·T AdragaoH H Malluche
Sep 9, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S A JamalP D Miller
Feb 3, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S A JamalC E Lok
Nov 15, 2006·International Urology and Nephrology·F Fevzi Ersoy
Dec 30, 2009·International Urology and Nephrology·Csaba AmbrusIstvan Mucsi
Jan 22, 2010·International Urology and Nephrology·Cs AmbrusI Mucsi
Mar 20, 2010·International Urology and Nephrology·Cs AmbrusI Mucsi
Nov 23, 2006·Current Osteoporosis Reports·Glenn A Ladinsky, Felix W Wehrli
Nov 16, 2012·Archives of Osteoporosis·Sasan MirfakhraeeUgis Gruntmanis
Mar 19, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Syazrah N SalamArif Khwaja
Jun 20, 2008·Kidney International·Thomas L NickolasElizabeth Shane
Nov 18, 2014·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Sarah L WestSophie A Jamal
May 3, 2007·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Sophie A JamalJoseph Beyene
Jan 1, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Sophie A JamalUNKNOWN Canadian Multicentre Osteoporosis Study Research Group
Sep 4, 2015·Seminars in Dialysis·Revekka Babayev, Thomas L Nickolas
Jan 15, 2009·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·UNKNOWN Guideline Working Group, Japanese Society for Dialysis Therapy
Apr 7, 2006·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Sophie A JamalDouglas C Bauer
Aug 2, 2011·Seminars in Dialysis·Stuart M Sprague
May 26, 2011·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Hartmut H MallucheMarie-Claude Monier-Faugere
Sep 17, 2013·Clinical Transplantation·Athanasios ChristoforidisFotios Papachristou
Mar 25, 2010·Seminars in Dialysis·Nigel D ToussaintPeter G Kerr
Oct 20, 2004·Advances in Chronic Kidney Disease·José R Weisinger, Ezequiel Bellorin-Font
Mar 12, 2015·Journal of Internal Medicine·S L WestS A Jamal
Sep 13, 2005·Renal Failure·A CrisafulliMichele Buemi
May 27, 2014·Journal of Bone and Mineral Metabolism·Chrysa GkogkaFotios Papachristou
Mar 7, 2015·Current Osteoporosis Reports·Sophie A Jamal, Thomas L Nickolas
Dec 6, 2014·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R C BucurS A Jamal
Jul 10, 2016·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A-J ChangN Chen
Nov 22, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Sarah L WestCharmaine E Lok
Jun 10, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Soichiro IimoriYusuke Tsukamoto
Apr 8, 2017·Journal of Nephrology·Pablo Antonio Ureña Torres, Martine Cohen-Solal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.