PMID: 18411080Sep 1, 1989Paper

Bone-derived proteins

Trends in Endocrinology and Metabolism : TEM
S Epstein

Abstract

The diagnosis and treatment of metabolic bone disease has been limited by a lack of understanding of bone cell physiology and of suitable markers for various bone cell functions in different diseases. The identification of noncollagenous proteins and their measurement in serum has added to our knowledge. At this stage, of all the bone-derived proteins, bone Gla protein (BGP) is apparently the most useful, but it is best used in conjunction with other tests. The diagnostic usefulness of other noncollagenous proteins, procollagen, and local factors still remains to be documented.

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Citations

Sep 1, 1993·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·J G ParthemoreL J Deftos

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