Bone graft in posterior spine fusion for adolescent idiopathic scoliosis: a meta-analysis

ANZ Journal of Surgery
Nathan KirznerAli Humadi

Abstract

The aim of this study was to systematically analyse and perform a meta-analysis on the current available literature comparing the fusion rates and complications associated with use of autograft, allograft and bone substitutes to supplement posterior spinal fusion for adolescent idiopathic scoliosis (AIS). The electronic databases including Embase, PubMed, Medline, Cinahl and Cochrane Library were searched to identify relevant studies. A total of 12 studies with 2389 patients were included for meta-analysis. The primary outcome was fusion rate, while the secondary outcomes included blood loss, operation time, infection rates and post-operative pain. The current meta-analysis found no difference in fusion rates between groups with an overall fusion rate of 100% (95% confidence interval (CI) 0.99-1.00; P < 0.05). Total estimated blood loss was significantly higher in the iliac crest bone graft (ICBG) group compared with control group (1018 versus 861 mL; P < 0.01). In addition, the mean operative time was significantly higher in the ICBG group (259 versus 237 min; P < 0.001). The ICBG group also had increased post-operative pain issues compared with the control group (26 versus 9%; P < 0.001). There was no significant difference i...Continue Reading

References

May 1, 1988·The Journal of Bone and Joint Surgery. British Volume·C A DoddD Thomas
Feb 1, 1980·The Journal of Bone and Joint Surgery. British Volume·M J McMaster
Feb 14, 1998·The Journal of Bone and Joint Surgery. British Volume·A O RansfordD Pries
Nov 22, 2001·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·M MuschikT Stoll
Feb 9, 2005·Journal of Spinal Disorders & Techniques·D Raymond KnappCharles T Price
Dec 17, 2008·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Thomas LernerUlf Liljenqvist
Feb 23, 2010·International Journal of Surgery·David MoherUNKNOWN PRISMA Group
Jan 17, 2014·Journal of Children's Orthopaedics·Markus Rafael KoniecznyRüdiger Krauspe
Dec 3, 2014·Pediatric Clinics of North America·Ron El-Hawary, Chukwudi Chukwunyerenwa
Aug 26, 2016·BMC Musculoskeletal Disorders·Yu-Cheng YehPo-Liang Lai

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Related Papers

European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
J RechtA Vincent
The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS
Sheraz R MarkarO J Wagner
© 2022 Meta ULC. All rights reserved