Bone grafting options in children

Spine
Randal R BetzAmer F Samdani

Abstract

Retrospective review of the literature. To review the current literature as well as recent trends in bone grafting techniques available for children. The currently accepted gold standard in bone grafting for adolescent idiopathic scoliosis (AIS) is autogenous iliac crest. Due to questions concerning complications such as donor site pain, other options have been explored, including various allograft sources, demineralized bone matrix, and bone morphogenetic protein. A review of the current medical literature was completed and additional case examples are presented. A review of the literature reveals that up to 31% of patients have persistent pain at 2 years post surgery when autogenous iliac crest bone graft is harvested. Allograft supplementation of local autograft has been demonstrated in the literature to be as effective as autogenous iliac crest bone grafting in contributing to a successful posterior spinal fusion in patients with AIS. Modern demineralized bone matrix formulations have been found in both animal models as well as in a recent retrospective clinical review to contribute to a successful posterior spinal fusion in AIS. Bone morphogenetic protein has been shown to contribute to a successful posterior spinal fusion...Continue Reading

References

May 1, 1988·The Journal of Bone and Joint Surgery. British Volume·C A DoddD Thomas
Jun 1, 1997·Clinical Orthopaedics and Related Research·J A GouletM L Greenfield
Sep 3, 1999·The Orthopedic Clinics of North America·T BoyceN Scarborough
Feb 29, 2000·Clinical Orthopaedics and Related Research·D M Ehrler, A R Vaccaro
Jul 6, 2000·The Orthopedic Clinics of North America·J E FlemingG F Muschler
Jan 24, 2002·Spine·Anne E HoltCharles G Greenough
Nov 1, 2003·The Spine Journal : Official Journal of the North American Spine Society·Alexander R VaccaroUNKNOWN North American Spine Society for Contemporary Concepts in Spine Care
Oct 7, 2004·The Journal of Bone and Joint Surgery. American Volume·Brett PetersonJay R Lieberman
Dec 29, 2004·The British Journal of Oral & Maxillofacial Surgery·P KesslerF W Neukam
Jul 5, 2005·The Journal of Bone and Joint Surgery. American Volume·Yongjung J KimKaren Steger-May
Nov 18, 2005·The Spine Journal : Official Journal of the North American Spine Society·Kenneth J H LeeJeffrey C Wang
Dec 3, 2005·The Journal of Bone and Joint Surgery. American Volume·Robert F McLainGeorge F Muschler
Jan 28, 2006·Journal of Pediatric Orthopedics·Amy N KagerPeter O Newton
Oct 4, 2006·The Journal of Bone and Joint Surgery. American Volume·David Skaggs
Feb 8, 2007·Archives of Pathology & Laboratory Medicine·Thomas W Bauer
Sep 23, 2008·The Spine Journal : Official Journal of the North American Spine Society·Thomas E MrozJeffrey C Wang
Dec 17, 2008·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Thomas LernerUlf Liljenqvist

❮ Previous
Next ❯

Citations

Sep 6, 2012·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Thomas Lerner, Ulf Liljenqvist
Sep 28, 2013·Revista española de cirugía ortopédica y traumatología·A MardomingoE Izquierdo
Nov 26, 2015·Journal of Pediatric Orthopedics·Robert F MurphyDaniel Hedequist
Feb 17, 2018·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Andrew J KobetsJohn K Houten
Jun 18, 2017·Spine Deformity·Matthew StreetJohn Ferguson
Apr 21, 2018·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Marco CrostelliCarlo Iorio
Jul 1, 2017·Spine Deformity·Matthew StreetJohn Ferguson
Jun 7, 2021·Journal of Pediatric Orthopedics·Alper YataganbabaPeter J Cundy

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.