PMID: 9555841Apr 29, 1998Paper

Bone healing of tibial lengthening is enhanced by hyperbaric oxygen therapy: a study of bone mineral density and torsional strength on rabbits

The Journal of Trauma
S W UengC H Shih

Abstract

We investigated the effect of intermittent hyperbaric oxygen (HBO) therapy on the bone healing of tibial lengthening in rabbits. Twelve male rabbits were divided into two groups of six animals each. The first group went through 2.5 atmospheres absolute of hyperbaric oxygenation for 2 hours daily, and the second group did not go through hyperbaric oxygenation. Each animal's right tibia was lengthened 5 mm using an uniplanar lengthening device. Bone mineral density (BMD) study was performed for all of the animals at 1 day before operation and at 3, 4, 5, and 6 weeks after operation. All of the animals were killed at 6 weeks postoperatively for biomechanical testing. Using the preoperative BMD as an internal control, we found that the BMD of the HBO group was increased significantly compared with the non HBO group. The mean %BMD at 3, 4, 5, and 6 weeks were 69.5%, 80.1%, 87.8%, and 96.9%, respectively, in HBO group, whereas the mean %BMD were 51.6%, 67.7%, 70.5%, and 79.2%, respectively, in non-HBO group (two tailed t test, p < 0.01, p < 0.01, p < 0.01, and p < 0.01 at 3, 4, 5, and 6 weeks, respectively). Using the contralateral nonoperated tibia as an internal control, we found that torsional strength of lengthened tibia of the H...Continue Reading

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Citations

Mar 23, 2010·BMC Musculoskeletal Disorders·Tsai-Sheng FuWen-Jer Chen
Jul 6, 2005·Theoretical Biology & Medical Modelling·Jacob BejarJochanan H Boss
Jul 20, 2010·Journal of Veterinary Emergency and Critical Care·Melissa L Edwards
Feb 3, 2015·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·J P GrassmannM Hakimi
Nov 6, 2003·Journal of Orthopaedic Trauma·Michael D McKeeEmil H Schemitsch
Aug 12, 2004·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Li-Jen YuanPaul Y Lin
Feb 6, 2007·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Wen-Ling YehSteve W N Ueng
Jun 15, 2007·Advances in Therapy·Levant EralpFeyza Unlu Ozkan
Feb 27, 2014·BMC Musculoskeletal Disorders·Song-Shu LinJan-Kan Chen
Dec 17, 2009·The Journal of Trauma·Oguz KucukdeveciSaduman B Adim
Mar 4, 2021·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·X F GongX B Wu
Mar 21, 2006·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Charles L ClarkDale A Baur
Feb 10, 2009·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Christopher J SalgadoKathryn A Kent

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