PMID: 8212953Jun 1, 1993Paper

Bone lesions of multiple myeloma in three dogs

Zentralblatt für Veterinärmedizin. Reihe A
H MaedaI Narama


Three cases of canine multiple myeloma that showed monoclonal IgA gammopathy and bone lesions were examined. One dog was associated with Bence-Jones proteinuria as well. Radiographic examination revealed extensive skeletal involvement of flat bones such as scapula, pelvic bone, costa, and epiphysis of long bones where the hematopoiesis was active throughout the life. Histopathologically, small osteolytic lesions occurred from periosteum and Haversian canal as well as endosteum, and larger lesions were formed by gradual expansion or fusion of small lesions. Osteolytic lesions did not necessarily involve tumor growth, explaining the inconsistent confirmation of tumor cells in biopsy specimens for diagnosis of multiple myeloma and suggesting the possible mechanism for osteolysis by some other humoral factors.


May 1, 1977·The Journal of Small Animal Practice·S K DorfmanA K Patnaik
Aug 27, 1987·The New England Journal of Medicine·I R GarrettG R Mundy
May 1, 1986·The American Journal of the Medical Sciences·E J Van SlyckM J Deegan
May 1, 1966·The Journal of Small Animal Practice·P PennockS E Olsson
May 1, 1981·The Veterinary Clinics of North America. Small Animal Practice·M A Thrall
Jan 1, 1982·The Journal of Small Animal Practice·J W Finnie, C R Wilks


Oct 3, 1999·Veterinary Immunology and Immunopathology·N C Pedersen
Sep 10, 2003·Journal of the American Veterinary Medical Association·Sarah J LautzenhiserRobert L Goring
Nov 26, 2008·Nature Clinical Practice. Gastroenterology & Hepatology·Ruchika GuttRalph R Weichselbaum
Oct 3, 2008·Journal of the American Veterinary Medical Association·Brigitte A Brisson, Marie-Claude Théoret
Feb 1, 1997·World Journal of Surgery·C SpertiS Pedrazzoli
Jun 18, 2002·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Makoto HiroiTakayuki Aimoto

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