Bone loss and the risk of non-vertebral fractures in women and men: the Tromsø study.

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
L A AhmedR M Joakimsen

Abstract

We assessed the association between the rate of forearm bone loss and non-vertebral fracture. Bone loss at the distal forearm predicted fractures, independently of baseline BMD, but not independently of follow-up BMD in women. The BMD level where an individual ends up is the significant predictor of fracture risk. Bone loss may predict fracture risk independently of baseline BMD. The influence of follow-up BMD on this prediction is unknown. The aim of this study was to assess the association between bone loss and fracture risk in both sexes in a prospective population-based study. We included 1,208 postmenopausal women (50 to 74 years), and 1,336 men (55 to 74 years) from the Tromsø Study, who had repeated distal and ultra-distal forearm BMD measurements. Non-vertebral fractures were registered from 2001 to 2005. A total of 100 women and 46 men sustained fractures during the follow-up time. Independent of baseline BMD, the RR associated with distal site bone loss of 1 SD %/year was 1.23 (1.01-1.50) for low-trauma fractures (excluding hand, foot, skull & high-trauma) and 1.32 (1.07-1.62) for osteoporotic fractures (hip, wrist and shoulder). However, bone loss did not predict fracture after adjusting for follow-up BMD. The BMD le...Continue Reading

References

Oct 1, 1990·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S L HuiC C Johnston
Feb 27, 1995·The American Journal of Medicine·B J Riis
Nov 1, 1995·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·K E EnsrudS R Cummings
Mar 1, 1996·The Journal of Clinical Endocrinology and Metabolism·M C ChapuyP J Meunier
Mar 1, 1996·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·P GarneroP D Delmas
Oct 1, 1996·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·P GarneroP D Delmas
Mar 1, 1997·The Journal of Clinical Endocrinology and Metabolism·P VergnaudP D Delmas
May 16, 1998·American Journal of Epidemiology·H BurgerH A Pols
Sep 17, 1998·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·T V NguyenJ A Eisman
May 18, 1999·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·P GarneroP D Delmas
Sep 24, 1999·The Journal of Clinical Investigation·S BassE Seeman
Dec 11, 1999·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·G K BerntsenV Fønnebø
Jan 26, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·L J MeltonB L Riggs
Apr 26, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·M T HannanD P Kiel
Aug 10, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·P GarneroP D Delmas
Oct 12, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·E Orwoll
Dec 7, 2000·Journal of Clinical Epidemiology·G K Rosvold BerntsenJ H Magnus
Dec 29, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·M T HannanD P Kiel
Feb 28, 2001·American Journal of Epidemiology·G K BerntsenJ H Magnus
Jun 8, 2001·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S GnudiC Ripamonti
Oct 19, 2001·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·L J MeltonR D Wasnich
Feb 16, 2002·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R M JoakimsenJ H Magnus
Jun 7, 2002·Lancet·Steven R Cummings, L Joseph Melton
Jul 12, 2002·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·O JohnellJ A Kanis
Aug 28, 2002·American Journal of Epidemiology·K E BainbridgeS D Harlow
Apr 18, 2003·Endocrinology and Metabolism Clinics of North America·Ego Seeman
Jun 24, 2003·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·L Joseph Melton
Nov 11, 2003·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Katie L StoneUNKNOWN Osteoporotic Fractures Research Group
Jun 9, 2004·Calcified Tissue International·J A KanisD Mellstrom
Dec 24, 2004·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·John A KanisNikolai Khaltaev
May 12, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Nina EmausV Fønnebø
Jun 9, 2005·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Tuan V NguyenJohn A Eisman
Oct 20, 2005·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Elisabeth Sornay-RenduPierre D Delmas
Dec 21, 2007·Journal of Bone and Mineral Metabolism·Ego Seeman
Aug 22, 2008·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Jane A CauleyUNKNOWN SOF Research Group
Oct 14, 2008·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Claudie BergerUNKNOWN CaMos Research Group

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Citations

Jul 27, 2014·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·K HolvikH E Meyer
Aug 6, 2015·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·W D LeslieL M Lix
Aug 4, 2011·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·E Michael LewieckiUNKNOWN FRAX® Position Development Conference Members
Jul 28, 2016·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·D SchrayC Kammerlander
Nov 15, 2016·Injury·Nick A JohnsonJ J Dias
Dec 10, 2016·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·William D LeslieLisa M Lix
Oct 4, 2014·Scandinavian Journal of Public Health·Anne Johanne SøgaardGrethe S Tell
Jan 25, 2018·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Lauren A BurtSteven K Boyd
Sep 13, 2014·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Richard EastellDennis M Black
Aug 24, 2019·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Albert ShiehArun S Karlamangla
Dec 2, 2019·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·X Xiao, Q Wu
Dec 28, 2017·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Tuan V Nguyen, John A Eisman
Dec 22, 2016·Innovative Surgical Sciences·Deborah SchrayCarl Neuerburg
Feb 18, 2016·Annals of the New York Academy of Sciences·Tsang-hai Huang, Gene P Ables
Apr 28, 2021·The Journal of Clinical Endocrinology and Metabolism·Albert ShiehGail A Greendale

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