PMID: 6977408Mar 1, 1982Paper

Bone marrow and blood involvement by lymphoma in relationship to the Lukes--Collins classification

Cancer
K FoucarR D Brunning

Abstract

The incidence, pattern, extent, and morphology of bone marrow involvement in 176 cases of non-Hodgkin's lymphoma (NHL) were studied in relationship to the Lukes--Collins classification. Ninety percent of the cases were B-cell lymphomas; 10% were T-cell lymphomas. In 53% of cases there was bone marrow involvement by lymphoma at diagnosis. Marrow involvement was most frequently found in the small lymphocyte (B), small cleaved follicular center cell (FCC), and convoluted lymphocyte lymphomas. Frequently, the extent of bone marrow biopsy replacement by lymphoma was less than 30%; the pattern of infiltration was predominantly focal (70%). Cytologic agreement between lymph node and bone marrow specimens was always present in small lymphocyte (B), small noncleaved FCC, convoluted lymphocyte, and lymphoepithelioid cell lymphomas. Cytologic diversity between lymph node and marrow was noted in 20% of small cleaved FCC, 40% (2/5) of large cleaved FCC, and 38% (3/8) of large noncleaved FCC lymphomas. In 79% of all involved cases, both bone marrow biopsy sections and aspirate smears were diagnostic of NHL; only biopsy sections were positive in 18%, and only smears were positive in 3%. The Lukes--Collins classification predicts a high incide...Continue Reading

References

Aug 1, 1975·Cancer·R W McKennaR D Brunning
Nov 1, 1978·American Journal of Clinical Pathology·R K BrynesR D Sundberg
Feb 1, 1966·The Journal of Experimental Zoology·R Rappaport
Oct 1, 1974·Cancer·R J Lukes, R D Collins
Apr 1, 1972·Cancer·S E JonesH S Kaplan

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Citations

Aug 1, 1992·Annals of Hematology·G Lambertenghi-DeliliersE E Polli
Oct 6, 2006·European Journal of Nuclear Medicine and Molecular Imaging·Niklaus G SchaeferThomas F Hany
Sep 3, 2011·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Yuki KagoyaKazuhito Hatanaka
May 15, 1986·Archives of Biochemistry and Biophysics·J L NgoK H Ibsen
Oct 4, 2011·International Journal of Molecular Imaging·Bingfeng TangChing Yee Oliver Wong
May 17, 2007·Acta Haematologica·Osnat Bairey, Ofer Shpilberg
Jul 9, 2004·The Tohoku Journal of Experimental Medicine·Atsushi HoshinoTakeshi Sasaki
Apr 1, 1989·Journal of Clinical Pathology·D M WhiteJ L Smith
Mar 1, 1984·Journal of Clinical Pathology·R BartlG Hoffmann-Fezer
Apr 1, 1993·Journal of Clinical Pathology·P W Bishop
Jan 1, 1997·Cancer Investigation·M R Bishop, A Kessinger
Mar 1, 1990·American Journal of Hematology·D J EllisonP K Pattengale
Feb 1, 1986·Clinics in Haematology·C R Singer, A H Goldstone
Jul 1, 2008·PET Clinics·Karen ChenDrew A Torigian
Dec 23, 2008·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Hani MawardiNathaniel Treister
Nov 14, 2002·American Journal of Clinical Pathology·Emina TorlakovicRichard D Brunning
Jan 1, 1991·Leukemia Research·P M ChenT J Chiou
Jun 1, 1988·British Journal of Haematology·R BartlR Burkhardt
Apr 6, 2002·Clinics in Laboratory Medicine·Antonio M Hernandez
Aug 1, 2015·Nuclear Medicine Communications·Elaine Yuen Phin LeePek-Lan Khong
Sep 23, 1997·American Journal of Hematology·C L BarekmanJ D Cotelingam
Jul 20, 2004·British Journal of Haematology·Danielle CanioniUNKNOWN Groupe d'Etude des Lymphomes Folliculaires
Oct 7, 2009·Virchows Archiv : an International Journal of Pathology·Deborah W SevillaGovind Bhagat

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