Bone marrow edema in traumatic vertebral compression fractures: Diagnostic accuracy of dual-layer detector CT using calcium suppressed images

European Journal of Radiology
Victor NeuhausJan Borggrefe

Abstract

To evaluate calcium suppressed images (CaSupp) in dual-layer detector computed tomography (DLCT) for the detection of bone marrow edema (BME) in vertebral fractures. The retrospective study was approved by the institutional review board. 34 patients with synchronous DLCT and MRI, who were diagnosed with one or more acute vertebral fractures, were included. MRI were systematically analyzed as reference standard. Two blinded and independent readers evaluated CaSupp for vertebral BME. Additionally, both readers determined the optimal calcium suppression indices (CaSupp-I) for visualization of BME in consensus and correlated the CaSupp-I with parallel measurement of trabecular density as surrogate parameter for bone mineral density. ROI-based measurements of the contrast-to-noise ratios (CNR) were also conducted. Interrater agreement was determined by kappa-statistics. CNR were analyzed using Wilcoxon signed rank test. Fifty-seven acute fractured vertebrae out of 383 vertebrae (14.9%) were found. CaSupp yielded an average sensitivity of 87% and specificity of 99%, a positive predictive value of 95%, a negative predictive value of 98% and an accuracy of 97% for the detection of fracture-associated edema. Interrater agreement was exc...Continue Reading

Citations

Dec 19, 2019·The Journal of International Medical Research·Xiaohuan ZhangZhiye Chen
Jun 3, 2020·Emergency Radiology·Aaron D SodicksonJennifer W Uyeda
Jan 8, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Anushri ParakhAvinash R Kambadakone
Feb 20, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Anushri ParakhAvinash R Kambadakone
Aug 6, 2021·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·Sam SedaghatOlav Jansen

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