PMID: 32672701Jul 17, 2020Paper

BONE METABOLISM AND BONE MINERAL DENSITY IN CHILDREN WITH RECURRENT BRONCHITIS

Georgian Medical News
L S OvcharenkoD Sheludko

Abstract

The aim - to determine the bone metabolism status and bone mineral density (BMD) in children with recurrent bronchitis (RB). 120 children aged 6 to 10 years were examined. Formed 2 groups: 1st group - children with RB (n=60); 2nd group - children occasionally suffering of upper respiratory tract infections (n=60). The average age was 8 years 2 months. Among children with RB, compared with children of the 2nd group, an increase in the number of patients with an increase in alkaline phosphatase activity (by 35.0%) (p<0.05), and serum osteocalcin level (by 66.7%) (p<0.05) was revealed, collagen type 1 degradation products (by 15.0%) (p<0.05), parathyroid hormone (by 13.3%) (p<0.05), decrease of serum 25(OH)D less than 30 ng/ml (by 59.3%) (p<0.05). A DXA in children with RB showed the presence of 24 (40.0%) episodes of decreased BMD in the L1, 25 (41.7%) episodes in L2, 24 (40.0%) episodes in L3, 27 (45.0%) episodes in L4, 28 (46.7%) cases in the left femur neck, 22 (36.7%) cases in the right femur neck. In children with RB was established activation of bone resorption on background of vitamin D deficiency and BMD decrease.

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Archives of Pediatrics & Adolescent Medicine
G RossL Preiser
Molecular and Cellular Biology
Deborah L BurkhartJulien Sage
© 2021 Meta ULC. All rights reserved