PMID: 9186219Jun 1, 1997Paper

Bone mineral changes during tibial fracture healing

Clinical Orthopaedics and Related Research
H C CattermoleJ L Cunningham

Abstract

The traditional assessment of fracture healing by manipulation and viewing of radiographs is subjective and qualitative. Dual energy x-ray absorptiometry by contrast provides an accurate, precise, and minimally invasive quantitative measure of bone mineral density, a property that shows strong correlations with various mechanical properties of bone. Fourteen patients with unilateral tibial shaft fractures stabilized by external fixation were monitored with dual energy x-ray absorptiometry at monthly intervals after fracture. Fractured and contralateral unfractured bones (controls) were scanned on each occasion. Changes in mineralization with time over the whole length of the fractured bone could be seen. The most pronounced effects were visible in the area of the fracture, with a minimum recorded fracture site bone mineral density of 38 +/- 13% of contralateral values, but often more long term alterations in bone mineral density affected regions at some distance from this zone. Significantly, in four patients who had scans 5 or more months after fracture, the mineralization at the fracture site had returned to control levels, whereas bone mineral density in a region proximal to the fracture showed evidence of persisting posttra...Continue Reading

References

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Citations

Apr 17, 1999·Journal of Orthopaedic Trauma·S E UtvågO Reikerås
Jan 12, 2000·Journal of Orthopaedic Trauma·N M Kurdy
Feb 16, 2008·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·T BieleckiT Szczepanski
Sep 30, 2008·Clinical Orthopaedics and Related Research·Neil Saran, Reggie C Hamdy
Feb 3, 2012·The Journal of Bone and Joint Surgery. American Volume·Dimitri CeroniNathalie Farpour-Lambert
Jan 26, 1999·Clinical Orthopaedics and Related Research·R A HaydaJ L Esterhai
Dec 14, 2011·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Giuliano BarbieriCláudio Henrique Barbieri
Oct 21, 2014·Acta ortopedica brasileira·Márcio Takey BezutiCláudio Henrique Barbieri
Jun 3, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J LeppäläM Järvinen
Dec 6, 2005·The Journal of Bone and Joint Surgery. British Volume·T FloerkemeierH Windhagen
Dec 20, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S W VeitchB M Ingle
Aug 19, 2009·HSS Journal : the Musculoskeletal Journal of Hospital for Special Surgery·Oladapo M BabatundeS Robert Rozbruch
Feb 27, 2009·Clinical Orthopaedics and Related Research·L E Claes, J L Cunningham
Aug 30, 2014·Journal of Pediatric Orthopedics·Dimitri CeroniVictor Dubois-Ferrière
Jan 11, 2019·Journal of Dental Research·M AriokaJ A Helms

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