PMID: 9536942Apr 16, 1998Paper

Bone mineral density and nutritional status in children with chronic inflammatory bowel disease

Gut
A M BootS M de Muinck Keizer-Schrama

Abstract

Osteoporosis has been reported in adult patients with inflammatory bowel disease. To evaluate bone mineral density (BMD), nutritional status, and determinants of BMD in children with inflammatory bowel disease. Fifty five patients (34 boys and 21 girls, age range 4-18) were studied; 22 had Crohn's disease and 33 ulcerative colitis. Lumbar spine and total body BMD, and body composition were assessed by dual energy x ray absorptiometry (DXA). Results were expressed as standard deviation scores (SDS). Lean body mass was also assessed by bioelectrical impedance analysis (BIA). Yearly measurements during two years were performed in 21 patients. The mean SDS of lumbar spine BMD and total body BMD were significantly lower than normal (-0.75 and -0.95, both p < 0.001). Height SDS and body mass index SDS were also decreased. The decrease in BMD SDS could not be explained by delay in bone maturation. The cumulative dose of prednisolone correlated negatively with lumbar spine BMD SDS (r = -0.32, p < 0.02). Body mass index SDS correlated positively with total body BMD SDS (r = 0.36, p < 0.02). Patients with Crohn's disease had significantly lower lumbar spine and total body BMD SDS than patients with ulcerative colitis, even after adjustme...Continue Reading

References

Mar 1, 1976·Archives of Disease in Childhood·J M Tanner, R H Whitehouse
Nov 1, 1976·Investigative Radiology·H K GenantL H Lanzi
Sep 1, 1992·Digestive Diseases and Sciences·F PigotB Amor
Jul 1, 1992·Radiology·E L van Persijn van MeertenS E Papapoulos
Feb 27, 1992·The New England Journal of Medicine·J S FinkelsteinA Klibanski
Sep 1, 1991·Calcified Tissue International·J Johnson, B Dawson-Hughes
Jan 1, 1990·Acta Paediatrica Scandinavica. Supplement·B S Kirschner
Apr 1, 1986·European Journal of Pediatrics·K Kruse, U Kracht
Feb 1, 1988·Baillière's Clinical Endocrinology and Metabolism·T J MartinG C Nicholson
Dec 1, 1988·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·A KönigH Fleisch
Apr 1, 1987·Gut·J E CompstonJ Rhodes
May 1, 1994·Clinical Endocrinology·A BlumsohnR Eastell
Jun 17, 1993·The New England Journal of Medicine·P SambrookJ Eisman
Nov 1, 1993·Journal of Pediatric Gastroenterology and Nutrition·R M IssenmanL Fraher
Dec 1, 1993·The Journal of Clinical Endocrinology and Metabolism·M E Cohen-SolalM C de Vernejoul
Jul 1, 1993·Gut·A M GriffithsP M Sherman
Oct 1, 1996·Annals of the Rheumatic Diseases·S Patel
Jan 1, 1997·The Journal of Clinical Endocrinology and Metabolism·A M BootS M de Muinck Keizer-Schrama
Jan 1, 1997·Archives of Disease in Childhood·J Allgrove
Apr 1, 1997·Archives of Disease in Childhood·F J CowanH R Jenkins

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Citations

Jan 9, 2007·Inflammatory Bowel Diseases·Francisco A SylvesterAnne M Griffiths
Jan 9, 2007·Inflammatory Bowel Diseases·Massimiliano PaganelliSalvatore Cucchiara
Feb 13, 2008·Inflammatory Bowel Diseases·Robert HeuschkelAnne Griffiths
Jul 29, 2009·Inflammatory Bowel Diseases·Susanne BechtoldSibylle Koletzko
Aug 5, 2010·Inflammatory Bowel Diseases·Alfreda KrupovesDevendra K Amre
Sep 28, 2010·Inflammatory Bowel Diseases·Michael D KappelmanRobert S Sandler
Apr 14, 2007·Pediatric Radiology·Larry A BinkovitzMaria J Henwood
Jul 3, 2008·Pediatric Radiology·Larry A BinkovitzPaul Sparke
Feb 5, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Mary B Leonard
Jan 5, 2011·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Wai W CheungRobert H Mak
Jan 1, 2008·Reviews in Endocrine & Metabolic Disorders·Anuradha Viswanathan, Francisco A Sylvester
May 8, 2003·Current Gastroenterology Reports·Manisha Harpavat, David J Keljo
Jun 14, 2005·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Adi CohenElizabeth Shane
Jun 7, 2005·The Journal of Nutritional Biochemistry·Stacey L CohenWendy E Ward
Apr 5, 2003·Best Practice & Research. Clinical Gastroenterology·Barbara Désir, Ernest G Seidman
Sep 16, 2011·The British Journal of Nutrition·Joanne F OliemanDick Tibboel
Oct 23, 2002·Alimentary Pharmacology & Therapeutics·E J LambA F Muller
May 7, 2004·Journal of Clinical Gastroenterology·Manisha HarpavatMiguel D Regueiro
Aug 21, 2002·Journal of Pediatric Gastroenterology and Nutrition·Arie LevineRaanan Shamir
Mar 27, 2003·Journal of Pediatric Gastroenterology and Nutrition·Arie LevineJames Markowitz
Jun 10, 2004·Journal of Pediatric Gastroenterology and Nutrition·Ronald E KleinmanUNKNOWN North American Society for Pediatric Gastroenterology, Hepatology And Nutrition
Jul 23, 2004·Journal of Pediatric Gastroenterology and Nutrition·Stefano Mora, Graziano Barera
Nov 11, 1999·Current Opinion in Pediatrics·F A Sylvester
Aug 24, 1999·Inflammatory Bowel Diseases·R M Issenman
Mar 27, 2003·Inflammatory Bowel Diseases·Johanna C EscherRichard J Grand
Mar 8, 2005·Journal of Pediatric Gastroenterology and Nutrition·Manisha HarpavatDavid J Keljo
Mar 30, 2005·Journal of Pediatric Gastroenterology and Nutrition·Lori J StarkJames Heubi
Jul 5, 2006·Journal of Pediatric Gastroenterology and Nutrition·Frank WaltherAnnette Findeisen
Jun 23, 2011·Journal of Pediatric Gastroenterology and Nutrition·Helen PappaCatherine Gordon
Apr 25, 2006·Archives of Disease in Childhood·R M BeattieR B Heuschkel
Jul 26, 2002·Archives of Disease in Childhood·T Mushtaq, S F Ahmed
Aug 21, 2013·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Dora LiuHarold Kim
Nov 3, 1998·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·M B LeonardV A Stallings
Aug 23, 2001·Journal of Pediatric Endocrinology & Metabolism : JPEM·I M van der Sluis, S M de Muinck Keizer-Schrama
Nov 3, 2006·Pediatrics·Helen M PappaRichard J Grand
Dec 10, 1999·Applied Human Science : Journal of Physiological Anthropology·K TeramotoS Komiya
May 31, 2011·Srpski arhiv za celokupno lekarstvo·Zoran LekovićDejan Nikolić
Apr 4, 2014·World Journal of Gastroenterology : WJG·Rebecca J Hill
Oct 18, 2013·European Journal of Pediatrics·Sze Choong WongMargaret Zacharin
Mar 5, 2014·Journal of Pediatric Gastroenterology and Nutrition·Peter J Porcelli, S Trent Rosenbloom
Mar 21, 2008·Digestive Diseases and Sciences·Letícia Helena Caldas LopesUlysses Fagundes-Neto

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