Bone mineral density in girls with forearm fractures

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Ailsa GouldingN J Lewis-Barned

Abstract

In childhood, the most common site of fracture is the distal forearm. To determine whether young girls with these fractures have low bone density more commonly than fracture-free controls, we measured bone density at the radius, spine, hip, and whole body and total body bone mineral content, lean tissue mass, and fat mass by dual-energy X-ray absorptiometry in 100 Caucasian girls aged 3-15 years with recent distal forearm fractures and 100 age- and gender-matched controls. Bone density (age-adjusted ratios of all cases:controls with 95% confidence intervals) was lower in cases at the ultradistal radius 0.963 (0.930-0.996), 33% radius 0.972 (0.945-0.999), lumbar spine 0.945 (0.911-0.980), hip trochanter 0.952 (0.918-0.988), and total body 0.978 (0.961-0.995). Moreover, osteopenia (defined as Z score below -1), was more common in cases than controls (p < 0.05) in the forearm, spine, and hip, with one third of fracture cases having low spinal density. Odds ratios (95% confidence intervals) for low bone density were: ultradistal radius, 2.2 (1.1-4.6); lumbar spine, L2-L4, 2.6 (1.3-4.9); and femur trochanter, 2.0 (1.0-3.9). Fracture patients aged 8-10 years weighed more (mean +/- SD) than age-matched controls (37.2+/-8.0 kg vs. 32.5...Continue Reading

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