Bone mineral density in patients beginning hemodialysis treatment

American Journal of Nephrology
B Pecovnik BalonM Kos

Abstract

Our study was designed to determine bone mineral density (BMD) in patients beginning hemodialysis (HD) treatment, a possible correlation with the duration of renal failure prior to treatment, a possible correlation with the basic disease and the association with the concentration of intact parathormone (iPTH). Our prospective clinical trial included 50 patients beginning HD treatment. Cortical bone mineral density (BMDc) was measured at the left femoral neck and trabecular bone mineral density (BMDt) in the region of the lumbosacral spine. Bone mineral density (BMD) was measured by quantitative digital radiography using a Hologic 2000 plus device belonging to the third generation of densitometers based on dual-energy X-ray absorptiometry. In patients (PTS) beginning HD, the average BMDc was 82 +/- 15% of BMDc in a healthy population of corresponding age and sex. The average BMDt was 91 +/- 16% of BMDt in a healthy population of corresponding age and sex. The difference was statistically significant (p < 0.05). There is a negative correlation between iPTH and BMDc r = -0.34 (p < 0.02). Patients with chronic glomerulonephritis (GN) had a statistically significantly higher BMDc (g/cm(2)) (p < 0.01) than those with analgetic nephro...Continue Reading

Citations

Nov 15, 2006·International Urology and Nephrology·F Fevzi Ersoy
May 5, 2005·American Journal of Nephrology·Nobuhiko JokiYoshihiko Imamura
Apr 17, 2012·Ultrasound in Medicine & Biology·Joanna ZywiecJanusz Gumprecht
Aug 2, 2005·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Paulo Gustavo Sampaio LacativaMaria Lucia Fleiuss de Farias
Dec 11, 2013·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Ivo ValkovskyZuzana Cermakova
Dec 22, 2005·Journal of Bone and Mineral Metabolism·Fettah Fevzi ErsoyDimitrios George Oreopoulos
May 26, 2004·The American Journal of Clinical Nutrition·Hope WeilerMalcolm Ogborn
Dec 2, 2017·Journal of Veterinary Internal Medicine·A ShipovG Segev

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