Bone-Protective Effects of Dried Plum in Postmenopausal Women: Efficacy and Possible Mechanisms

Nutrients
Bahram H ArjmandiNeda S Akhavan

Abstract

Osteoporosis is an age-related chronic disease characterized by a loss of bone mass and quality, and is associated with an increased risk of fragility fractures. Postmenopausal women are at the greatest risk of developing osteoporosis due to the cessation in ovarian hormone production, which causes accelerated bone loss. As the demographic shifts to a more aged population, a growing number of postmenopausal women will be afflicted with osteoporosis. Certain lifestyle factors, including nutrition and exercise, are known to reduce the risk of developing osteoporosis and therefore play an important role in bone health. In terms of nutrition, accumulating evidence suggests that dried plum (Prunus domesticaL.) is potentially an efficacious intervention for preventing and reversing bone mass and structural loss in an ovariectomized rat model of osteoporosis, as well as in osteopenic postmenopausal women. Here, we provide evidence supporting the efficacy of dried plum in preventing and reversing bone loss associated with ovarian hormone deficiency in rodent models and in humans. We end with the results of a recent follow-up study demonstrating that postmenopausal women who previously consumed 100 g dried plum per day during our one-ye...Continue Reading

References

Dec 1, 1991·Bone and Mineral·D N Kalu
Mar 1, 1990·The Journal of Clinical Investigation·I R GarrettG R Mundy
Nov 1, 1987·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·F H NielsenJ R Hunt
Apr 1, 1995·Biological Trace Element Research·C D YeeH W Sampson
Nov 1, 1994·Environmental Health Perspectives·F H Nielsen
Dec 16, 1998·The American Journal of Clinical Nutrition·B H ArjmandiS C Kukreja
Feb 5, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·N E LaneJ H Kinney
Mar 2, 1999·Biological Trace Element Research·R E ChapinH McCoy
Nov 25, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·M N Horcajada-MolteniJ P Barlet
Jun 13, 2001·Critical Reviews in Food Science and Nutrition·M Stacewicz-SapuntzakisN R Farnsworth
Aug 31, 2001·Menopause : the Journal of the North American Menopause Society·J KayserA Pressman
Feb 28, 2002·Journal of Women's Health & Gender-based Medicine·Bahram H ArjmandiRobert A Wild
Jun 13, 2002·Journal of Agricultural and Food Chemistry·Shin-Ichi KayanoNobuji Nakatani
Jul 5, 2002·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Roman C MühlbauerAndreas Reinli
Jul 19, 2002·JAMA : the Journal of the American Medical Association·Jacques E RossouwUNKNOWN Writing Group for the Women's Health Initiative Investigators
Sep 26, 2003·Calcified Tissue International·L A J L M BraamC Vermeer
Nov 11, 2003·The Journal of Nutrition·Roman C MühlbauerHerbert Wetli
Dec 4, 2003·Journal of the American Dietetic Association·MacKenzie L DismoreSarah L Booth
Aug 24, 2004·Current Pharmaceutical Design·Jun IwamotoYoshihiro Sato
Jan 5, 2005·BioFactors·Takahisa Tokunaga
Nov 10, 2005·Menopause : the Journal of the North American Menopause Society·Farzad DeyhimBahram H Arjmandi
Dec 3, 2005·The Journal of Clinical Investigation·Lawrence G Raisz
Jul 14, 2006·Menopause : the Journal of the North American Menopause Society·Latha DevareddyBahram H Arjmandi
Aug 22, 2006·Biochemical Pharmacology·Irfan RahmanPaul A Kirkham
Dec 6, 2006·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Russel BurgeAnna Tosteson
Aug 30, 2007·Cellular and Molecular Life Sciences : CMLS·D E Stevenson, R D Hurst
Oct 24, 2007·The Journal of Nutrition·Kevin D Cashman
Mar 11, 2008·The Journal of Nutritional Biochemistry·Latha DevareddyBahram H Arjmandi
Mar 28, 2008·Nutrition Reviews·Forrest H Nielsen
Oct 29, 2008·Evidence-based Complementary and Alternative Medicine : ECAM·Catherine D JohnsonBahram H Arjmandi
Nov 15, 2008·Clinical Journal of the American Society of Nephrology : CJASN·Bart Clarke
Mar 12, 2009·Ageing Research Reviews·Shirin Hooshmand, Bahram H Arjmandi
Aug 27, 2010·The Journal of Nutrition·Bernard P HalloranBrenda J Smith
May 21, 2011·Orthopaedic Nursing·Mary KamienskiMarielos Vega
Jul 9, 2011·The British Journal of Nutrition·Shirin HooshmandBahram H Arjmandi
May 23, 2012·Journal of Agricultural and Food Chemistry·Kieran M TuohyRoberto Viola
Aug 8, 2012·Therapeutic Advances in Musculoskeletal Disease·Oddom DemontieroGustavo Duque
Aug 30, 2013·Journal of Translational Medicine·Gillian WheaterJacob M van Laar

❮ Previous
Next ❯

Citations

Dec 5, 2019·Journal of Alzheimer's Disease : JAD·Cansu AgcaYuksel Agca
Nov 16, 2019·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Joseph L Roberts, Hicham Drissi
Apr 2, 2020·International Journal of Molecular Sciences·Timothy E L DouglasAndre G Skirtach
Apr 18, 2020·Scientific Reports·Sonette SteczinaAnn-Sofie Schreurs
Aug 15, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A Di IorioL Ferrucci
Jul 18, 2019·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Nishikant RautGail B Mahady
Mar 31, 2021·Journal of Animal Science and Biotechnology·Sanjeev WastiBirendra Mishra
Jun 3, 2021·Nutrients·Wojciech SłupskiBeata Nowak
Nov 13, 2021·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Ruiqiang LiYuxia Ma

❮ Previous
Next ❯

Methods Mentioned

BETA
hormone replacement therapy

Software Mentioned

Google Scholar

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Menopause : the Journal of the North American Menopause Society
Farzad DeyhimBahram H Arjmandi
Journal of Women's Health & Gender-based Medicine
Bahram H ArjmandiRobert A Wild
Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
J A PascoM A Kotowicz
© 2022 Meta ULC. All rights reserved