Bone relapse in acute lymphoblastic leukemia

Indian Journal of Pediatrics
K S PadmanjaliL S Arya

Abstract

Acute lymphoblastic leukemia (ALL) can occasionally relapse in unusual extramedullary sites like bone. Here we present a 6.5-year old boy with 'T' cell ALL who developed a swelling in left tibia which was infiltrated with lymphoblasts 7 months after completion of chemotherapy. Bone marrow and cerebrospinal fluid were negative for blasts. This is the first reported case of bone relapse in ALL from India. We discuss the previous cases of isolated bone relapse in ALL reported in English literature.

References

Jan 1, 1988·Medical and Pediatric Oncology·E FriedmanB Ramot
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Jan 1, 1986·The American Journal of Pediatric Hematology/oncology·M L Bernstein, S Schwartz
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Jan 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M SmithR Ungerleider
Aug 8, 1998·British Journal of Haematology·J M Chessells

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Citations

Mar 5, 2016·Mycoses·Sarah A SchmalzleDavid J Riedel
Sep 29, 2018·Oxford Medical Case Reports·Jagdish Prasad MeenaRachna Seth

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