Bone response to a novel highly porous surface in a canine implantable chamber

Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Sally R FrenkelTian Hua

Abstract

Long-term survival of uncemented hip components is dependent upon successful biological fixation. This study examined a new prosthetic surface treatment consisting of a highly porous open structure of commercially pure titanium, Tritanium Dimensionalized Metal; its overall porosity is approximately 65-70%. With the use of an implantable chamber in dogs, the effects of this treatment on bone ingrowth and strength of attachment were compared to both titanium (overall porosity of 30-35%) and cobalt chrome beads (overall porosity of 35-40%), with and without hydroxyapatite coating. At 6 and 12 weeks, chambers were explanted and specimens underwent high-resolution radiographic imaging and mechanical testing. At 12 weeks, Tritanium surfaces had greater bone penetration and tensile strength than remaining surface types. Over 40% of the Tritanium specimens had a tensile strength greater than 500 N, exceeding the testing capability of the servohydraulic equipment. The highly porous Tritanium surfaces allow for a far greater amount of bone ingrowth than beaded surfaces, and may create a geometry that enhances mechanical strength. Tritanium Dimensionalized Metal surface treatment may result in a clinically valuable implant fixation surfac...Continue Reading

References

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Nov 6, 2002·Journal of Biomedical Materials Research·Sally R FrenkelJohn L Ricci

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Citations

Nov 20, 2012·Indian Journal of Orthopaedics·Christos G PaganiasGeorge A Macheras
Apr 9, 2013·The Journal of Arthroplasty·R Michael Meneghini, Brian C de Beaubien
Mar 5, 2013·Journal of the Mechanical Behavior of Biomedical Materials·N HarrisonP Mc Donnell
May 12, 2009·The Journal of Arthroplasty·Merrill A Ritter, R Michael Meneghini
Oct 20, 2010·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Karen B SagomonyantsGloria Gronowicz
May 31, 2013·The Journal of Arthroplasty·Nicholas A BeckmannRudi G Bitsch
Aug 21, 2018·Orthopedics·Jared M NewmanMichael A Mont
Jan 29, 2008·Clinical Orthopaedics and Related Research·Andras HeijinkJean D Sibonga
Feb 7, 2017·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Emil S VutescuSumon Nandi
Oct 31, 2009·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Manjunath RamappaAndrew Port
Jun 6, 2020·Scientific Reports·Bernd WegenerPeter Quadbeck
Nov 28, 2019·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Souptick ChandaDilip Kumar Pratihar

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