PMID: 15379419Sep 24, 2004Paper

Bone speed of sound in infants of mothers with gestational diabetes mellitus

Journal of Pediatric Endocrinology & Metabolism : JPEM
Rivka H RegevIta Litmanovitz

Abstract

Bone strength in infants of mothers with gestational diabetes mellitus (IGDM) was reported to be either decreased or unaltered. However, no report using quantitative ultrasound measurement of speed of sound (QUS-SOS) for bone strength assessment has been published. The aim of the present study was to assess bone strength by QUS-SOS measurements in IGDM in comparison to healthy matched full-term infants. Nineteen IGDM and 18 healthy controls participated in the study. Postnatal tibial bone SOS was measured by Sunlight Omnisense. Mean birth weight (BW) of IGDM (3,587.6+/-148.6 g) was higher compared to the control infants (3,311.1+/-74.5 g), but this difference was not statistically significant. Mean bone SOS was significantly lower in IGDM (2,976.7+/-27.2 m/sec) compared to the control infants (3,093.3+/-23.6 m/sec; p <0.003). There was a significant negative correlation between bone SOS and BW in all the study participants (r = -0.32, p <0.025). No significant difference in BW and bone SOS was noted between infants with postnatal hypoglycemia and normoglycemia. There was no correlation between maternal HbA1c during pregnancy and neonatal bone SOS. Bone strength was significantly decreased in IGDM compared to healthy controls. N...Continue Reading

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Citations

Sep 6, 2011·Early Human Development·Gal Dubnov-RazAyala Maayan-Metzger
Aug 19, 2007·Journal of Perinatology : Official Journal of the California Perinatal Association·M TshornyD Mandel
Jun 15, 2007·Journal of Perinatology : Official Journal of the California Perinatal Association·M ChenJ D Carver
Feb 5, 2009·Journal of Pediatric Endocrinology & Metabolism : JPEM·Tugba GursoyGulsevin Tekinalp
Feb 28, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Evrim Kıray BaşBanu Kuran
Oct 11, 2019·Journal of Pediatric Endocrinology & Metabolism : JPEM·Marvin MillerDavid Ayoub
Aug 21, 2014·Maternal and Child Health Journal·Irit Schushan-EisenTzipora Strauss
Jul 22, 2019·Current Diabetes Reports·Elvira Isganaitis

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