Boomerang sign: Clinical significance of transient lesion in splenium of corpus callosum.

Annals of Indian Academy of Neurology
Hardeep Singh MalhotraPawan Kumar Sharma

Abstract

Transient signal abnormality in the splenium of corpus callosum on magnetic resonance imaging (MRI) is occasionally encountered in clinical practice. It has been reported in various clinical conditions apart from patients with epilepsy. We describe 4 patients with different etiologies presenting with signal changes in the splenium of corpus callosum. They were diagnosed as having progressive myoclonic epilepsy (case 1), localization-related epilepsy (case 2), hemicrania continua (case 3), and postinfectious parkinsonism (case 4). While three patients had complete involvement of the splenium on diffusion-weighted image ("boomerang sign"), the patient having hemicrania continua showed semilunar involvement ("mini-boomerang") on T2-weighted and FLAIR image. All the cases had noncontiguous involvement of the splenium. We herein, discuss these cases with transient splenial involvement and stress that such patients do not need aggressive diagnostic and therapeutic interventions. An attempt has been made to review the literature regarding the pathophysiology, etiology, and outcome of such lesions.

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Mar 8, 2014·The Indian Journal of Radiology & Imaging·Aamish Z KaziAmit S Ghawate
Aug 28, 2013·Journal of Neurology, Neurosurgery, and Psychiatry·Matti HillbomMaurizio A Leone
Jul 19, 2014·Neurology India·Thomas MathewRaghunandan Nadig
Mar 10, 2016·Neurology India·Bhupender K BajajShweta Pandey
Feb 17, 2015·Journal of Neurology·Rajendra Singh JainRakesh Agrawal
Dec 20, 2014·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Chellamani HariniSanjeev V Kothare
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Jul 4, 2017·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Sung Eun ParkMi Jung Park
Jan 1, 2020·World Journal of Clinical Oncology·Christopher Robert D'AngeloJulie Chang
Jan 19, 2020·BMC Medical Imaging·Maryam Haghighi-MoradLeila Ahmad-Molaei
Jul 13, 2021·Curēus·Boby Varkey MaramattomHanna A Meleth
Oct 27, 2020·The Indian Journal of Radiology & Imaging·Shailendra S NaikAtul Sharma

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