Boron neutron capture therapy for glioblastoma: is it worth pursuing?

Technology in Cancer Research & Treatment
Ute Linz

Abstract

Presently glioblastomas are incurable brain tumors. The prospect of treating this deadly disease has been the major justification for the current programs of boron neutron capture therapy (BNCT) throughout the world. However, based on pharmacological and cell biological considerations, it is improbable that BNCT will ever be an effective therapy for this tumor. Indeed, a review of the published literature over the last 50 years fails to provide justification for developing BNCT past its present experimental stage.

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Citations

Jan 31, 2009·IEEE/ACM Transactions on Computational Biology and Bioinformatics·Simone Linz, Charles Semple
Aug 25, 2015·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Martti KulvikJuha Jääskeläinen
Jan 13, 2012·Bulletin of Experimental Biology and Medicine·L A MostovichE V Grigor'eva
Sep 17, 2010·Journal of Medicinal Chemistry·Louis M Rendina

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