Botulinum toxin for the treatment of refractory erythema and flushing of rosacea

Dermatology : International Journal for Clinical and Investigative Dermatology
Kui Young ParkChang Kwun Hong

Abstract

Persistent erythema and severe rosacea flushing can cause significant physical discomfort and emotional stress to patients. Currently, no satisfactory treatments are available. We report two cases of refractory flushing and erythema of rosacea that were successfully treated with intradermal botulinum toxin injections. Good cosmetic results were achieved for both patients. The side effects during and after treatment were mild pain and localized bruising; these symptoms resolved within several days without further treatment. Intradermal botulinum toxin injection may be an effective treatment for refractory erythema and rosacea flushing that deserves further study in a larger patient population.

Citations

Apr 8, 2017·Aesthetic Surgery Journal·Joel SchlessingerJoely Kaufman
Oct 13, 2018·Lasers in Surgery and Medicine·Or FriedmanOfir Artzi
Mar 1, 2020·Journal of Cosmetic Dermatology·Ji Yeon HongKui Young Park
Feb 29, 2020·Clinical, Cosmetic and Investigational Dermatology·Burhan EnginServer Serdaroğlu
Jul 3, 2020·Dermatologic Therapy·Rungsima WanitphakdeedechaWoraphong Manuskiatti
May 2, 2018·Seminars in Immunopathology·Jae Eun Choi, Anna Di Nardo
Feb 4, 2021·Journal of Cosmetic Dermatology·Hanlin ZhangQiuning Sun
Feb 11, 2021·Toxins·Emanuela MartinaAnnamaria Offidani
Apr 20, 2021·Journal of Cosmetic Dermatology·Or FriedmanAdriano Mesquita Bento
May 8, 2021·Clinical, Cosmetic and Investigational Dermatology·Hanlin ZhangQiuning Sun
Sep 4, 2021·Dermatology and Therapy·Mark C Marchitto, Anna L Chien
Sep 15, 2021·Archives of Dermatological Research·Edith HannaVince Bertucci

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