Botulinum toxin injection for lower urinary tract dysfunction

International Journal of Urology : Official Journal of the Japanese Urological Association
Yue-Chen Kuo, Hann-Chorng Kuo

Abstract

Botulinum toxin has been recently accepted as a novel treatment for lower urinary tract dysfunctions refractory to conventional treatment. Review of the clinical trials in recent years, botulinum toxin type A has been widely used in the urethra or urinary bladder to treat voiding dysfunction due to detrusor sphincter dyssynergia, incontinence due to neurogenic or idiopathic detrusor overactivity, sensory disorders such as bladder hypersensitivity, overactive bladder, and interstitial cystitis/painful bladder syndrome. Intravesical botulinum toxin type A injection is effective in treatment of urinary incontinence due to detrusor overactivity in men and women, as well as in children. Currently botulinum toxin type A has also been applied to treat lower urinary tract symptoms due to benign prostatic hyperplasia in patients not suitable for surgery. This article reviewed the recent advances of botulinum toxin type A on lower urinary tract dysfunction.

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Citations

Feb 14, 2016·Neurourology and Urodynamics·Ann T Hanna-MitchellGeorgi V Petkov
Nov 14, 2015·Journal of Clinical Biochemistry and Nutrition·Daisuke YamaguchiRyuichi Iwakiri
Nov 7, 2012·International Journal of Urology : Official Journal of the Japanese Urological Association·Katsuya HikitaAtsushi Takenaka
Jun 20, 2015·Advances in Chronic Kidney Disease·Lara S MacLachlan, Eric S Rovner
Feb 11, 2014·Age and Ageing·William Gibson, Adrian Wagg
Jul 29, 2018·Naunyn-Schmiedeberg's Archives of Pharmacology·F Aura KullmannLori A Birder
Nov 23, 2019·PloS One·Lina Birgitta IvarssonAnnika Kristina Lindström
Dec 15, 2020·Current Opinion in Pediatrics·Abbie Bauer

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