Bovine chronic besnoitiosis in a calf: Characterization of a novel B. besnoiti isolate from an unusual case report

Veterinary Parasitology
C Diezma-DíazGema Álvarez-García

Abstract

Bovine besnoitiosis, caused by the apicomplexan Besnoitia besnoiti, is a chronic and debilitating disease characterized by cutaneous and systemic manifestations that primarily affects adult beef cattle. Previous studies have reported that clinical besnoitiosisis is rare in calves. However, we isolated B. besnoiti from a chronically infected calf for the first time. The identity of the Besnoitia species was determined after parasite isolation and molecular genotyping. According to the results obtained in vitro the new isolate, named as Bb-Spain3, was characterized in a reproducible in vitro model and was categorized as a low invader and low prolific isolate with a slower lytic cycle compared to Bb-Spain 1 isolate. Specific traits that differentiate isolates obtained from adult animals from those infecting calves were not found. Next, we described the first case report of chronic besnoitiosis in a female calf less than 6 months-old with a low body condition. The disease was confirmed by the presence of specific anti-B. besnoiti antibodies and parasite detection in the skin. At post-mortem examination, tissue samples were collected for histological, immunohistochemical and molecular analyses. DNA-parasite was detected in 31 differ...Continue Reading

Citations

Sep 5, 2019·Transboundary and Emerging Diseases·Carlos Diezma-DíazGema Álvarez-García
Aug 14, 2018·Transboundary and Emerging Diseases·Carlos Diezma-DíazGema Álvarez-García
Nov 7, 2019·Parasites & Vectors·Alejandro Jiménez-MeléndezGema Álvarez-García
Dec 31, 2019·Veterinary Parasitology·Carlos Diezma-DíazGema Álvarez-García

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