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Bovine herpesvirus tegument protein VP22 enhances thymidine kinase/ganciclovir suicide gene therapy for neuroblastomas compared to herpes simplex virus VP22

Journal of Virology

Apr 1, 2004

Zhao-hua QiuGary A Splitter

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Abstract

Herpesvirus tegument protein VP22 can enhance the effect of therapeutic proteins in gene therapy, such as thymidine kinase (tk) and p53; however, the mechanism is unclear or controversial. In this study, mammalian expression vectors carrying bovine herpesvirus 1 (BHV-1) VP22 (BVP22) or ...read more

Mentioned in this Paper

Transfection
Shuttle Vectors
Therapeutic protein
Study
Simplexvirus
Evaluation
Human herpes simplex virus
Genetic Therapy, Somatic
Protein p53
Glycoprotein D, Equid herpesvirus 4
Paper Details
References
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    • Citations12
    • References28
    • Citations12
  • Bovine herpesvirus tegument protein VP22 enhances thymidine kinase/ganciclovir suicide gene therapy for neuroblastomas compared to herpes simplex virus VP22

    Journal of Virology

    Apr 1, 2004

    Zhao-hua QiuGary A Splitter

    PMID: 15047837

    DOI: 10.1128/jvi.78.8.4224-4233.2004

    Abstract

    Herpesvirus tegument protein VP22 can enhance the effect of therapeutic proteins in gene therapy, such as thymidine kinase (tk) and p53; however, the mechanism is unclear or controversial. In this study, mammalian expression vectors carrying bovine herpesvirus 1 (BHV-1) VP22 (BVP22) or ...read more

    Mentioned in this Paper

    Transfection
    Shuttle Vectors
    Therapeutic protein
    Study
    Simplexvirus

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    Paper Details
    References
    • References28
    • Citations12
    • References28
    • Citations12
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