Bovine pericardium in treating large corneal perforation secondary to alkali injury: a case report.

Indian Journal of Ophthalmology
Rajesh K Khanna, Ezanee Mokhtar

Abstract

To describe use of a locally processed bovine pericardium (BP) to cover a large central corneal perforation following alkali injury and discuss postoperative outcome. A 27-year-old Malay male patient presented two weeks after alkali splashed in his left eye while working. A clinical diagnosis of left central corneal ulcer with limbal ischemia following alkali injury with secondary infection was made. After failed medical therapy, we performed a Gunderson conjunctival flap under local anesthesia that retracted after one week and resulted in a large central corneal perforation with surrounding stromal thinning. The perforation was covered with a locally processed BP xenograft (Lyolemb) supplied by the National Tissue Bank, University Sains Malaysia. Nine months follow-up showed a well-taken graft without any exposure/dehiscence and minimal inflammation. Amniotic membrane transplantation when used as a patch graft needs an urgent tectonic graft to promote corneal stability in patients with severe corneal thinning. The use of processed BP can be a viable option in treating such cases.

References

May 20, 1999·Ophthalmic Surgery and Lasers·D R Jordan, S R Klapper
Dec 3, 1999·Klinika oczna·J Markuszewska, P Krzyzanowska
Apr 26, 2002·The British Journal of Ophthalmology·J S Mehta, W A Franks

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Citations

Jan 23, 2013·The Annals of Thoracic Surgery·Yuan-Ming TsaiChing Tzao
Feb 1, 2011·Annals of Vascular Surgery·Xin LiAlan Dardik
Mar 27, 2010·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Chungkwon YooHyo-Myung Kim
Mar 8, 2011·Korean journal of urology·Seung Jin MoonHong Sang Moon
Dec 21, 2017·International Ophthalmology·Konstantinos DroutsasNikolaos Mamas
Dec 19, 2018·JFMS Open Reports·Pablo Pérez López, Stefania Martinoli

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Methods Mentioned

BETA
scraping
xenograft

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