Bovine x mouse hybridomas that secrete bovine immunoglobulin G1

Science
S SrikumaranR A Goldsby

Abstract

The interspecific fusion of normal bovine lymphocytes with a nonsecreting mouse hybridoma produced stable cell lines secreting bovine immunoglobulins. One of these lines has continued to secrete immunoglobulin G1 (5 to 10 micrograms per milliliter) for over 16 months. The bovine x mouse hybrid cells can be expected to provide bovine monoclonal immunoglobulins for sequencing studies and for use as serological standards as well as to provide messenger RNA for cloning bovine immunoglobulin genes.

References

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Citations

Jan 1, 1991·Archives of Virology·D V OniskM L Frey
Jan 1, 1988·Developmental and Comparative Immunology·A R Arulanandam, R A Goldsby
Mar 1, 1984·Veterinary Immunology and Immunopathology·S SrikumaranR A Goldsby
Jun 1, 1987·Veterinary Immunology and Immunopathology·D V AndersonP Porter
Dec 1, 1987·Veterinary Immunology and Immunopathology·R A GoldsbyA J Guidry
Jul 1, 1989·Veterinary Immunology and Immunopathology·K H Nielsen, M D Henning
Nov 30, 1989·Veterinary Immunology and Immunopathology·D J Groves, E M Tucker
Jan 6, 2004·International Ophthalmology Clinics·Mark A Latina, Vikas Gulati

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