Bowel Damage at Diagnosis Using the Lémann Index Score in Saudi Arabian Patients With Crohn's Disease

Curēus
Hajar HalawaniMahmoud Mosli

Abstract

Background Advanced bowel damage caused by Crohn's disease (CD) in the form of strictures and penetrating lesions has been associated with future surgical resection. However, in general, the degree of bowel damage in patients with CD is not examined at the time of diagnosis, and the natural history of CD may differ phenotypically between patients from Arabic countries as compared to patients from Europe and North America. Thus, we aimed to assess the degree of structural bowel damage in Saudi Arabian CD patients at diagnosis. We used the Lémann Index (LI) score, an instrument that measures cumulative digestive tissue damage by magnetic resonance enterography (MRE) and endoscopy, to establish any possible association between the duration of symptoms and the degree of bowel damage. Method This retrospective study was conducted by reviewing the data of all CD patients following up at King Abdulaziz University Hospital (KAUH) that were investigated by endoscopy and MRE at baseline. MRE-LI was calculated by scoring previous surgery, disease location and extension, and intestinal complications. A LI score of >2.0 was set as the cut-off point for bowel damage. Descriptive statistics were used to provide an overview of demographic and ...Continue Reading

References

Dec 21, 2000·The British Journal of Surgery·O BernellG Hellers
Dec 17, 2008·Scandinavian Journal of Gastroenterology·Catherine LolyEdouard Louis
Oct 29, 2009·The American Journal of Gastroenterology·Laurent Peyrin-BirouletWilliam J Sandborn
Aug 21, 2010·Inflammatory Bowel Diseases·Laurent Peyrin-BirouletWilliam J Sandborn
May 12, 2011·Inflammatory Bowel Diseases·Benjamin ParienteMarc Lémann
May 3, 2014·Inflammatory Bowel Diseases·Mohammad I El MouzanSami Wali
Mar 15, 2015·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Cyrielle GillettaJacques Cosnes
Jan 9, 2016·Journal of Crohn's & Colitis·Gionata FiorinoSilvio Danese
Nov 1, 2016·Journal of Crohn's & Colitis·Uri Kopylov, Rami Eliakim
Jul 12, 2017·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Aida Kapic LunderUNKNOWN IBSEN Study Group
Jan 18, 2018·Diseases of the Colon and Rectum·Wei LiuQingwen Xie
Aug 24, 2018·Journal of Crohn's & Colitis·Christian MaaserUNKNOWN European Crohn’s and Colitis Organisation [ECCO] and the European Society of Gastrointestinal and Abdominal Radiology [ESGAR

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surgical resection
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