Bowel dysfunction after sigmoid resection underestimated: Multicentre study on quality of life after surgery for carcinoma of the rectum and sigmoid

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
M van HeinsbergenJoop L M Konsten

Abstract

The Low Anterior Resection Syndrome (LARS) severely affects quality of life (QoL) after rectal cancer surgery. There are no data about functional complaints after sigmoid cancer surgery. We investigated LARS and QoL in patients with a resection for sigmoid cancer versus patients who had surgery for rectal cancer. 506 patients after resection for rectal or sigmoid cancer who were at least one year colostomy-free were included between January 2008 and December 2013. Bowel function was assessed by the LARS-Score. QoL was assessed by the EORTC QLQ-C30 and -CR29 questionnaires. QoL was compared between the LARS score categories and tumour height categories. 412 respondents (81.5%) could be included for the analyses. The median interval since treatment was 5 years, and the median age at the follow-up point was 72 years. Major LARS increased significantly with decreasing tumour height from one fifth in sigmoid carcinoma to 90% in low rectum carcinoma. Female gender (OR = 2.162; 95% CI: 1.349-3.467), postoperative temporary diverting stoma (OR = 3.457; 95% CI: 2.019-5.919) and tumours located in the middle (OR = 3.193; 95% CI: 1.696-6.010) or lower rectum (OR = 8.247; 95% CI: 1.672-40.678) were independently associated with the develop...Continue Reading

Citations

Jul 19, 2019·Diseases of the Colon and Rectum·Joost A G van der HeijdenAdriana J G Maaskant-Braat
Jul 26, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M van HeinsbergenJ L Konsten
Aug 10, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M van HeinsbergenJ L Konsten
Jan 17, 2020·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C KeaneJ Woodfield
Apr 10, 2020·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·H EssangriA Souadka
Jul 24, 2020·Zentralblatt für Chirurgie·Christian Rainer BeltzerRoland Schmidt
Dec 6, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Sanne J VerkuijlEdgar J B Furnée
Oct 15, 2020·BMC Gastroenterology·Hajar EssangriAmine Souadka
May 26, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Sophie A PilkingtonKaren P Nugent
Jul 24, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Rui SunYi Xiao

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