Brachial plexus magnetic resonance imaging differentiates between inflammatory neuropathies and does not predict disease course

Brain and Behavior
Bas A JongbloedLeonard H van den Berg

Abstract

The main objective of this study was to evaluate the correlation between the distribution of brachial plexus magnetic resonance imaging (MRI) abnormalities and clinical weakness, and to evaluate the value of brachial plexus MRI in predicting disease course and response to treatment in multifocal motor neuropathy (MMN), Lewis-Sumner syndrome (LSS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Sixty-seven patients with an inflammatory neuropathy diagnosed at our tertiary referral center for neuromuscular diseases had undergone bilateral T2-weighted short tau inversion recovery (STIR) MRI of the brachial plexus. We obtained clinical follow-up data and scored all MRIs for abnormalities and the symmetry of their distribution. Brachial plexus MRI abnormalities were detected in 45% of the patients. An abnormal MRI did not predict disease course in terms of patterns of weakness, sensory disturbances or response to treatment. Within the spectrum of radiological abnormalities, asymmetrical clinical syndromes, MMN and LSS were significantly associated with asymmetrical radiological abnormalities, whereas symmetrical abnormalities predominated in CIDP (p < .001, phi 0.791). T2 STIR brachial plexus MRI abnormalities ...Continue Reading

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Citations

Aug 14, 2018·Current Opinion in Neurology·Katie BeadonJean-Marc Léger
Aug 29, 2018·Current Opinion in Neurology·H Stephan GoedeeLeonard H van den Berg
Nov 16, 2018·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·G FargeotC Labeyrie
Jul 28, 2019·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·F JomierP Lozeron
Oct 2, 2019·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·G FargeotK Viala
Sep 13, 2019·Journal of Neurology, Neurosurgery, and Psychiatry·Wei Zhen YehBruce V Taylor
Feb 6, 2020·Muscle & Nerve·Marieke H J van RosmalenW Ludo van der Pol
Sep 24, 2020·Journal of Neurology·Marieke H J van RosmalenW Ludo van der Pol
Oct 2, 2020·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Brian M Gilcrease-GarciaMatthew S Parsons
Oct 2, 2020·Continuum : Lifelong Learning in Neurology·Kelly Gwathmey
Mar 21, 2020·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Xiaoyun SuChuansheng Zheng
Oct 20, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Raffi TopakianJohannes Trenkler
Feb 26, 2021·Muscle & Nerve·Dev NathaniMatthew C Kiernan
Nov 7, 2020·Brain : a Journal of Neurology·Filip EftimovCamiel Verhamme
Apr 29, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Johan A TellemanLeo H Visser

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