PMID: 3769769Oct 1, 1986Paper

Bradycardia due to trihexyphenidyl hydrochloride

Drug Intelligence & Clinical Pharmacy
R BlumensohnH Munitz

Abstract

A chronic schizophrenic patient was treated with an anticholinergic drug, trihexyphenidyl hydrochloride. The patient developed, paradoxically, sinus bradycardia. The reaction was specific to trihexyphenidyl and not to other anticholinergic drugs. This antidyskinetic drug is widely used in clinical psychiatric practice and physicians should be aware of this side effect.

References

Jul 1, 1977·The American Journal of Psychiatry·K Macvicar
Sep 22, 1973·The Medical Journal of Australia·L G KilohS E Williams
Mar 4, 1972·British Medical Journal·Z Friedman, E Neumann
Mar 1, 1971·Clinical Pharmacology and Therapeutics·P Dauchot, J S Gravenstein

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Citations

Jul 1, 1992·Annals of Saudi Medicine·N A Qureshi
Sep 8, 2016·Proceedings of the National Academy of Sciences of the United States of America·Yinglong MiaoCeline Valant
Jul 28, 2004·Journal of Clinical Forensic Medicine·Thair Suleiman AL-Nsour, Kamal A Hadidi

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