Brain abscess due to Panton-Valentine leukocidin-positive Staphylococcus aureus.

Infection
A RamosI Sánchez

Abstract

Panton-Valentine leukocidin (PVL) is a cytotoxin produced by Staphylococcus aureus that exhibits highly specific lytic activity against polymorphonuclear cells, monocytes, and macrophages. A 34-year-old man admitted for right parietal brain abscess and thickened dura mater in close proximity to a lytic bone lesion is presented. The abscess culture yielded methicillin-sensitive S. aureus that produced PVL. The patient did well after surgery and antibiotic treatment. A hematogenous infection, route of bone infection with progression to dura mater and brain parenchyma was hypothesized. To our knowledge this is the first reported case of a brain abscess due to PVL-positive S. aureus.

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Citations

Jan 1, 2011·BMJ Case Reports·Marilina AntonelouParveen Sharma
Aug 8, 2009·Future Microbiology·John M Atack, David J Kelly
Apr 18, 2019·Dermatology : International Journal for Clinical and Investigative Dermatology·Danuta Nowicka, Ewelina Grywalska

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