PMID: 9661950Nov 20, 1998Paper

Brain abscesses caused by Burkholderia pseudomallei

The Journal of Infection
A PadiglioneD Spelman

Abstract

Burkholderia pseudomallei is an important human pathogen in tropical areas, particularly South East Asia and Northern Australia. A fatal case of meliodosis presenting as brain abscesses is described. The patient deteriorated despite treatment and died 21 days after admission. Burkholderia pseudomallei was only isolated after administration of corticosteroids, whilst on treatment with antibiotics to which the organism later showed in vitro sensitivity. Magnetic resonance imaging was more sensitive than computed tomography in diagnosing early brainstem infection in this patient. Physicians working outside the endemic areas must be attuned to the possibility of melioidosis in any patient with an appropriate history of travel to endemic areas. The combination of striking early, extensive, confluent T2 hyperintensity with disproportionately small enhancing lesions may be characteristic of meliodosis.

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Citations

Apr 3, 2002·Transactions of the Royal Society of Tropical Medicine and Hygiene·D R ChadwickC C Lee
Jun 19, 2013·Journal of Neurosurgery·Matthew L VestalIan F Dunn
Feb 5, 2008·Journal of Neurosurgery·G Samson Sujit KumarVedantam Rajshekhar
Aug 11, 2015·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·C C HsuRobert Norton
Oct 28, 2015·Journal of Travel Medicine·Michael Dan
Feb 18, 2016·World Neurosurgery·Chun-Chieh LiangSzu-Ting Chen
Mar 30, 2017·The Journal of International Medical Research·Yuefu ZhanAnle Yu

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