Brain edema: induction in cortical slices by polyunsaturated fatty acids

Science
P H Chan, R A Fishman

Abstract

The presence of polyunsaturated and saturated fatty acids in leukocytic membranes prompted study of their possible role in the induction of brain edema. Polyunsaturated fatty acids including sodium arachidonate, sodium linoleate, sodium linolenate, and docasahexaenoic acids induced edma in slices of rat brain cortex. This cellular edema was specific, since neither saturated fatty acids nor a fatty acid containing a single double bond had such effect.

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Related Concepts

Cortex Bone Disorders
Tissue Membrane
Adrenal Cortex Diseases
Linolenate
Linoleate
Structure of Cortex of Kidney
Leukocytes
Saturated Fat
Water-Electrolyte Imbalance
Granulocyte

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