Brain Injury Lesion Imaging Using Preconditioned Quantitative Susceptibility Mapping without Skull Stripping

AJNR. American Journal of Neuroradiology
Salil SomanY Wang

Abstract

Identifying cerebral microhemorrhage burden can aid in the diagnosis and management of traumatic brain injury, stroke, hypertension, and cerebral amyloid angiopathy. MR imaging susceptibility-based methods are more sensitive than CT for detecting cerebral microhemorrhage, but methods other than quantitative susceptibility mapping provide results that vary with field strength and TE, require additional phase maps to distinguish blood from calcification, and depict cerebral microhemorrhages as bloom artifacts. Quantitative susceptibility mapping provides universal quantification of tissue magnetic property without these constraints but traditionally requires a mask generated by skull-stripping, which can pose challenges at tissue interphases. We evaluated the preconditioned quantitative susceptibility mapping MR imaging method, which does not require skull-stripping, for improved depiction of brain parenchyma and pathology. Fifty-six subjects underwent brain MR imaging with a 3D multiecho gradient recalled echo acquisition. Mask-based quantitative susceptibility mapping images were created using a commonly used mask-based quantitative susceptibility mapping method, and preconditioned quantitative susceptibility images were made u...Continue Reading

References

Sep 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·M A BernsteinN J Pelc
Oct 21, 2004·JAMA : the Journal of the American Medical Association·Chelsea S KidwellSteven Warach
Dec 20, 2005·Lancet Neurology·Guohua XiJulian T Hoff
Jan 24, 2009·Lancet Neurology·Steven M GreenbergUNKNOWN Microbleed Study Group
Mar 24, 2009·Journal of Magnetic Resonance Imaging : JMRI·Jaladhar NeelavalliE Mark Haacke
Dec 3, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ludovic de RochefortYi Wang
Sep 4, 2010·Journal of Magnetic Resonance Imaging : JMRI·E M HaackeY C N Cheng
Apr 3, 2012·Neurosurgical Focus·Prachi MehndirattaWarren R Selman
Aug 2, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jianqi LiYi Wang
Jun 8, 2013·AJNR. American Journal of Neuroradiology·S SomanK W Yeom
Jul 22, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Yi Wang, Tian Liu
Jun 18, 2016·Current Treatment Options in Neurology·Eric JouventHugues Chabriat
Jul 29, 2016·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Zhe LiuPascal Spincemaille

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