Brain mapping of digestive sensations elicited by cortical electrical stimulations
Abstract
The aim of the study was to obtain a comprehensive map of cortical areas from where digestive sensations during intracerebral electrical stimulations (ES) in epileptic patients are elicited. Direct cortical ESs were performed in 339 medically intractable epileptic patients selected to presurgical evaluation using chronically stereotaxically implanted intracerebral electrodes and audio-video-EEG monitoring system. Digestive sensations were electrically induced on 723 different anatomical sites in 172 subjects (51%). According to the exclusion criteria, the final analysis includes 174 relevant stimulations evoked in 87 patients. The reported sensations referred predominantly to the upper part of the digestive tract including the epigastria and area over the periumbilical (n = 83; 48%), retrosternal (n = 17; 10%), pharyngeal (n = 31; 18%) and oral (n = 18; 10%) regions. The temporal pole (BA 38), hippocampus, amygdala and anterior cingulate cortex (ACC; BA 24/BA 32) were the typical anatomical locations connected with epigastric sensations. Retrosternal sensations were preferentially related to the ACC, while oro-pharyngeal sensations were most related to the suprasylvian opercular cortex and the insula. Cortical ESs are followed ...Continue Reading
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Electrical Stimulation Mapping of Brain Function: A Comparison of Subdural Electrodes and Stereo-EEG
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