Jul 20, 2016

Brain perfusion: computed tomography and magnetic resonance techniques

Handbook of Clinical Neurology
William A CopenOtto Rapalino


Cerebral perfusion imaging provides assessment of regional microvascular hemodynamics in the living brain, enabling in vivo measurement of a variety of different hemodynamic parameters. Perfusion imaging techniques that are used in the clinical setting usually rely upon X-ray computed tomography (CT) or magnetic resonance imaging (MRI). This chapter reviews CT- and MRI-based perfusion imaging techniques, with attention to image acquisition, clinically relevant aspects of image postprocessing, and fundamental differences between CT- and MRI-based techniques. Correlations with cerebrovascular physiology and potential clinical applications of perfusion imaging are reviewed, focusing upon the two major classes of neurologic disease in which perfusion imaging is most often performed: primary perfusion disorders (including ischemic stroke, transient ischemic attack, and reperfusion syndrome), and brain tumors.

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Mentioned in this Paper

Ischemic Cerebrovascular Accident
In Vivo
Ischemic Attack
Magnetic Resonance Imaging
X-Ray Computed Tomography
Cerebrovascular Physiology
Imaging Techniques
Transient Ischemic Attack

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