Brain responsivity to emotional faces differs in men and women with and without a history of alcohol use disorder.

PloS One
Marlene Oscar-BermanKayle S Sawyer

Abstract

Inclusion of women in research on Alcohol Use Disorder (AUD) has shown that gender differences contribute to unique profiles of cognitive, emotional, and neuropsychological dysfunction. We employed functional magnetic resonance imaging (fMRI) of abstinent individuals with a history of AUD (21 women [AUDw], 21 men [AUDm]) and demographically similar non-AUD control (NC) participants without AUD (21 women [NCw], 21 men [NCm]) to explore how gender and AUD interact to influence brain responses during emotional processing and memory. Participants completed a delayed match-to-sample emotional face memory fMRI task, and brain activation contrasts between a fixation stimulus and pictures of emotional face elicited a similar overall pattern of activation for all four groups. Significant Group by Gender interactions revealed two activation clusters. A cluster in an anterior portion of the middle and superior temporal gyrus, elicited lower activation to the fixation stimulus than to faces for the AUDw as compared to the NCw; that abnormality was more pronounced than the one observed for men. Another cluster in the medial portion of the superior frontal cortex elicited higher activation to the faces by AUDm than NCm, a difference that was...Continue Reading

References

Sep 1, 1975·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·G G Briggs, R D Nebes
Jun 1, 1990·Alcoholism, Clinical and Experimental Research·M Oscar-BermanD A Weber
Sep 7, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S ThesenL R Schad
Mar 29, 2001·Brain Research. Cognitive Brain Research·M L Kesler-WestL X Blonder
Oct 6, 2001·Brain Research. Cognitive Brain Research·J NarumotoY Yonekura
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Sep 27, 2003·Journal of Cognitive Neuroscience·T Jason Druzgal, Mark D'Esposito
Dec 5, 2003·Cerebral Cortex·Bruce FischlAnders M Dale
Dec 16, 2003·Cognitive, Affective & Behavioral Neuroscience·Fionnuala C MurphyAndrew D Lawrence
Apr 13, 2004·Nature Neuroscience·Kalanit Grill-SpectorNancy Kanwisher
Feb 18, 2005·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jennifer UekermannUlrich Trenckmann
Feb 17, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Florin Dolcos, Gregory McCarthy
May 9, 2007·Neuropsychology·Uraina S ClarkMichael Pencina
Aug 21, 2007·Neuropsychologia·Andrew D Engell, James V Haxby
Sep 18, 2007·Neuropsychology Review·Marlene Oscar-Berman, Ksenija Marinković
Apr 4, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Matthew L LoPrestiChantal E Stern
Apr 11, 2008·Annals of the New York Academy of Sciences·Randy L BucknerDaniel L Schacter
May 12, 2009·Behavioural Brain Research·Jodene Goldenring FineDavid C Zhu
Jun 17, 2009·Human Brain Mapping·Theodore D SatterthwaiteJames Loughead
Jul 4, 2009·NeuroImage·Douglas N Greve, Bruce Fischl
Aug 14, 2009·Alcoholism, Clinical and Experimental Research·Ksenija MarinkovicGordon J Harris
Dec 4, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Carissa L PhilippiDavid Rudrauf
Mar 3, 2010·Social Cognitive and Affective Neuroscience·Michelle L KeightleyCheryl L Grady
Nov 3, 2010·Lancet·David J NuttUNKNOWN Independent Scientific Committee on Drugs
May 4, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Christopher P SaidAlexander Todorov
Nov 1, 2011·Annual Review of Clinical Psychology·Susan Nolen-Hoeksema
Jan 17, 2012·Neuropsychologia·M E Kret, B De Gelder
Jun 26, 2012·Alcoholism, Clinical and Experimental Research·Susan Mosher RuizGordon J Harris
Nov 26, 2013·Neuropsychiatric Disease and Treatment·Riya B LuharMarlene Oscar-Berman
Oct 14, 2014·Handbook of Clinical Neurology·Marlene Oscar-BermanZoe R Gravitz
Oct 14, 2014·Handbook of Clinical Neurology·Sara Jo NixonBen Lewis
Jan 13, 2015·Alcoholism, Clinical and Experimental Research·Mary M ValmasMarlene Oscar-Berman

❮ Previous
Next ❯

Software Mentioned

Destrieux
Matlab scripts
Annot
FAST
Freesurfer
Presentation
Matlab
glmfit
FS
mri

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.