Brain rust: recent discoveries on the role of oxidative stress in neurodegenerative diseases

Nutritional Neuroscience
Diêgo Madureira de OliveiraRamon Santos El-Bachá

Abstract

Oxidative stress (OS) and damages due to excessive reactive oxygen species (ROS) are common causes of injuries to cells and organisms. The prevalence of neurodegenerative diseases (ND) increases with aging and much of the research involving ROS and OS has emerged from works in this field. This text reviews some recent published articles about the role of OS in ND. Since there are many reviews in this field, the focus was centered in articles published recently. The Scientific Journals Directory supported by the Brazilian Ministry of Education Office for the Coordination of Higher Educational Personnel Improvement (CAPES) was used to search, download, and review articles. The search engine looked for the terms 'oxidative stress AND neurodegenerative diseases AND nutrition' in 10 different scientific collections. Biochemical markers for ND lack sensitivity or specificity for diagnosis or for tracking response to therapy today. OS has an intimate connection with ND, albeit low levels of ROS seem to protect the brain. Deleterious changes in mitochondria, OS, calcium, glucocorticoids, inflammation, trace metals, insulin, cell cycle, protein aggregation, and hundreds to thousands of genes occur in ND. The interaction of genes with th...Continue Reading

References

Oct 6, 2000·Life Sciences·R S El-BacháA Minn
Feb 18, 2005·NeuroRx : the Journal of the American Society for Experimental NeuroTherapeutics·Stanley Fahn, David Sulzer
Feb 18, 2005·NeuroRx : the Journal of the American Society for Experimental NeuroTherapeutics·Michael C Irizarry
Feb 18, 2005·NeuroRx : the Journal of the American Society for Experimental NeuroTherapeutics·Nathan Pankratz, Tatiana Foroud
Sep 15, 2005·Biochemistry·Ian V J MurrayPaul H Axelsen
Dec 8, 2005·Experimental Parasitology·A M PinheiroM F D Costa
Jul 4, 2006·NeuroRx : the Journal of the American Society for Experimental NeuroTherapeutics·Thomas J MontineJing Zhang
Jul 4, 2006·NeuroRx : the Journal of the American Society for Experimental NeuroTherapeutics·D Allan ButterfieldTanea Reed
Jan 24, 2007·Toxicon : Official Journal of the International Society on Toxinology·A M M SilvaS L Costa
Mar 18, 2008·Critical Care : the Official Journal of the Critical Care Forum·Hülya Bayir, Valerian E Kagan
Mar 18, 2008·Current Opinion in Chemical Biology·Kevin J Barnham, Ashley I Bush
Mar 3, 2009·Advanced Drug Delivery Reviews·Bernadett Kalmar, Linda Greensmith
Dec 17, 2009·Methods in Molecular Biology·Vittorio CalabreseD Allan Butterfield
Jan 26, 2010·Human & Experimental Toxicology·D M de OliveiraR S El-Bachá
Mar 4, 2010·BMC Medical Genetics·Malin von OtterHenrik Zetterberg
May 14, 2010·Journal of Alzheimer's Disease : JAD·Maria ManczakP Hemachandra Reddy
Jun 11, 2010·Neurochemical Research·Athan BailletGérard Besson
Jun 23, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Barry J SnowUNKNOWN Protect Study Group
Aug 3, 2010·Biochimica Et Biophysica Acta·Weilin XieKenny K K Chung
Sep 21, 2010·Journal of the Neurological Sciences·J M Morillas-RuizM L Vidal-Guevara
Nov 9, 2010·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Dae-Hee LeeYong J Lee
Nov 20, 2010·Journal of Psychopharmacology·John T O'BrienUNKNOWN BAP Dementia Consensus Group
Dec 7, 2010·Neurotoxicology·Gabriela A Salvador, Patricia I Oteiza
Dec 21, 2010·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Mi-Jeong KimHo-Geun Yoon
Dec 22, 2010·Orphanet Journal of Rare Diseases·Raymund A C Roos
Jan 8, 2011·Human Molecular Genetics·Saskia SchmidtHermann Lübbert
Jan 25, 2011·Nature Reviews. Cancer·Rob A CairnsTak W Mak
Feb 8, 2011·Free Radical Biology & Medicine·Tomasz M Stępkowski, Marcin K Kruszewski
Feb 9, 2011·Toxicology Letters·Hyun Joo KwonGi Ryang Kweon
Feb 12, 2011·The Biochemical Journal·Simon V Avery
Mar 3, 2011·Nature Cell Biology·Ira Tabas, David Ron
Mar 19, 2011·Toxicology·Klaudia Jomova, Marian Valko
Apr 2, 2011·The Journal of Biological Chemistry·Yi WenShao-Hua Yang

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Citations

Aug 7, 2013·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Jerrold PetrofskyRakhi Save
Nov 13, 2013·Cellular and Molecular Life Sciences : CMLS·Hjalte Holm AndersenTorben Moos
Apr 15, 2016·International Journal of Preventive Medicine·Akram SadeghiZahra Hejazi
Apr 16, 2016·Immunity & Ageing : I & a·Sergio DavinelliGiovanni Scapagnini
Apr 10, 2013·The Journal of International Medical Research·Jian-min LiangPeng-fei Ge
Sep 25, 2017·Perspectives on Psychological Science : a Journal of the Association for Psychological Science·Peter Kramer, Paola Bressan
Nov 8, 2018·The Journal of Endocrinology·Ebony T GilbreathPuliyur S MohanKumar
Apr 5, 2018·Technology and Health Care : Official Journal of the European Society for Engineering and Medicine·Min-Ki LeeNamju Lee

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