Brain-to-brain coupling during handholding is associated with pain reduction

Proceedings of the National Academy of Sciences of the United States of America
P GoldsteinS G Shamay-Tsoory

Abstract

The mechanisms underlying analgesia related to social touch are not clear. While recent research highlights the role of the empathy of the observer to pain relief in the target, the contribution of social interaction to analgesia is unknown. The current study examines brain-to-brain coupling during pain with interpersonal touch and tests the involvement of interbrain synchrony in pain alleviation. Romantic partners were assigned the roles of target (pain receiver) and observer (pain observer) under pain-no-pain and touch-no-touch conditions concurrent with EEG recording. Brain-to-brain coupling in alpha-mu band (8-12 Hz) was estimated by a three-step multilevel analysis procedure based on running window circular correlation coefficient and post hoc power of the findings was calculated using simulations. Our findings indicate that hand-holding during pain administration increases brain-to-brain coupling in a network that mainly involves the central regions of the pain target and the right hemisphere of the pain observer. Moreover, brain-to-brain coupling in this network was found to correlate with analgesia magnitude and observer's empathic accuracy. These findings indicate that brain-to-brain coupling may be involved in touch-r...Continue Reading

References

Apr 1, 1995·Journal of Developmental and Behavioral Pediatrics : JDBP·T Field
Oct 1, 1994·Journal of Personality and Social Psychology·L K Acitelli, T C Antonucci
Oct 1, 1996·Brain Research. Brain Research Reviews·J R Augustine
Jan 5, 2000·Pediatrics·L GrayE M Blass
Oct 6, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·T P JungT J Sejnowski
Jan 10, 2004·Integrative Cancer Therapies·Janice Post-WhiteIrving Lerner
Mar 16, 2004·Proceedings of the National Academy of Sciences of the United States of America·Jean-Philippe BrunetJill P Mesirov
Jun 23, 2004·Behavioral Medicine·Karen M GrewenKathleen C Light
Jun 24, 2004·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Garrick L WallstromNathan A Fox
Jul 1, 2006·Science·Dale J LangfordJeffrey S Mogil
Aug 30, 2006·Emotion·Matthew J HertensteinAriane R Jaskolka
Oct 4, 2006·Progress in Brain Research·Johanna KisslerCornelia Herbert
Oct 5, 2006·The Journal of Pain : Official Journal of the American Pain Society·Claudio BabiloniPaolo Maria Rossini
Jan 5, 2007·Psychological Science·James A CoanRichard J Davidson
Jan 9, 2007·Cerebral Cortex·Ilaria BufalariSalvatore Maria Aglioti
Mar 30, 2007·Brain Research·Philipp Kanske, Sonja A Kotz
May 2, 2007·Proceedings of the National Academy of Sciences of the United States of America·Emmanuelle TognoliJ A Scott Kelso
Jun 7, 2007·Annual Review of Psychology·Frans B M de Waal
Jun 27, 2007·Psychological Bulletin·Robert J GatchelDennis C Turk
Oct 4, 2007·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Jean Decety, Claus Lamm
Mar 21, 2008·Nature Reviews. Neuroscience·Barry E Stein, Terrence R Stanford
Apr 3, 2008·Human Brain Mapping·Frank Van Overwalle
May 14, 2008·Current Pain and Headache Reports·Raymond C Tait
Aug 23, 2008·Brain Research·Yan MuShihui Han
Sep 23, 2008·The Clinical Journal of Pain·Nathalie GauthierMichael J L Sullivan
Sep 23, 2008·The Clinical Journal of Pain·Annmarie CanoJaclyn B Heller
Nov 11, 2008·Neuroscience and Biobehavioral Reviews·Alberto Gallace, Charles Spence
Mar 5, 2009·Nature Reviews. Neuroscience·Jeffrey S Mogil
Mar 19, 2009·BMC Neuroscience·Ulman LindenbergerViktor Müller
Apr 3, 2009·Journal of Neurophysiology·A Mouraux, G D Iannetti
Sep 23, 2009·Experimental Brain Research·India MorrisonHåkan Olausson
Feb 9, 2010·Developmental Science·Ruth FeldmanOrna Zagoory
May 5, 2010·Proceedings of the National Academy of Sciences of the United States of America·Marleen B SchippersChristian Keysers

❮ Previous
Next ❯

Citations

Aug 29, 2018·Human Brain Mapping·Ann-Kathrin KreuderDirk Scheele
Sep 25, 2018·Social Cognitive and Affective Neuroscience·Mariana von MohrAikaterini Fotopoulou
Feb 13, 2019·Social Cognitive and Affective Neuroscience·Kelong Lu, Ning Hao
Mar 1, 2019·Scientific Reports·Yulia GollandNava Levit-Binnun
May 30, 2019·Nature Reviews. Neuroscience·Elizabeth Redcay, Leonhard Schilbach
Aug 14, 2019·Perspectives on Psychological Science : a Journal of the Association for Psychological Science·Simone G Shamay-Tsoory, Avi Mendelsohn
Mar 5, 2020·Social Cognitive and Affective Neuroscience·Stefanie HoehlAnnett Schirmer
May 21, 2020·Proceedings. Biological Sciences·Philip PärnametsAndreas Olsson
Apr 18, 2020·Social Cognitive and Affective Neuroscience·Marianne C ReddanTor D Wager
May 10, 2020·Social Cognitive and Affective Neuroscience·Jonathan LevyRuth Feldman
Apr 9, 2020·Psychological Research·Katia MattarozziAlexander Todorov
Apr 13, 2018·Frontiers in Psychology·Francisco J Parada, Alejandra Rossi
May 30, 2020·PLoS Computational Biology·Yuval HartL Mahadevan
May 12, 2020·Frontiers in Psychiatry·Yafeng Pan, Xiaojun Cheng
Jun 18, 2020·Neuroscience of Consciousness·Ana Lucía Valencia, Tom Froese
Jun 27, 2019·Pain·Marina López-SolàTor D Wager
Oct 18, 2019·Frontiers in Psychology·Gabriela MarkovaStefanie Hoehl
Jul 12, 2020·Neuroscience and Biobehavioral Reviews·Martin Picard, Carmen Sandi
Dec 18, 2020·Frontiers in Psychiatry·Jonathan Levy, Oren Bader
Jan 29, 2021·Frontiers in Human Neuroscience·Julia C BassoRachel Rugh
Oct 9, 2020·Social Cognitive and Affective Neuroscience·Anaël AyrollesGuillaume Dumas
Feb 25, 2021·The International Journal of Social Psychiatry·Debanjan BanerjeeTs Sathyanarayana Rao
Mar 13, 2021·Frontiers in Psychology·Stefanella Costa-CordellaAlejandra Rossi
Feb 25, 2020·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Madison LongPascal Vrtička
May 8, 2021·Frontiers in Psychology·Allan N Schore
May 7, 2021·Annals of the New York Academy of Sciences·Viktor MüllerUlman Lindenberger
May 13, 2021·Journal of Neuropsychology·Larissa L MeijerH Chris Dijkerman
May 18, 2021·The American Journal of Clinical Hypnosis·Yeganeh Farahzadi, Zoltan Kekecs
Jun 9, 2021·Social Cognitive and Affective Neuroscience·Carolyn Parkinson
Jul 18, 2021·Neuroscience and Biobehavioral Reviews·Viktor MüllerUlman Lindenberger
Aug 10, 2021·Frontiers in Psychiatry·Elena Kozakevich ArbelUri Hertz
Jul 22, 2021·Psychophysiology·Yair Dor-ZidermanYulia Golland

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Palliative Medicine
Paul C Rousseau, Gerald Blackburn
The Journal of Pain : Official Journal of the American Pain Society
P GoldsteinI Weissman-Fogel
Indian Journal of Occupational and Environmental Medicine
Anjali Mahajan
© 2022 Meta ULC. All rights reserved