Brain Volumes at Term-Equivalent Age in Preterm Infants: Imaging Biomarkers for Neurodevelopmental Outcome through Early School Age

The Journal of Pediatrics
Kristin KeunenManon J N L Benders

Abstract

To evaluate the relationship between brain volumes at term and neurodevelopmental outcome through early school age in preterm infants. One hundred twelve preterm infants (born mean gestational age 28.6 ± 1.7 weeks) were studied prospectively with magnetic resonance imaging (imaged at mean 41.6 ± 1.0 weeks). T2- and T1-weighted images were automatically segmented, and volumes of 6 tissue types were related to neurodevelopmental outcome assessed using the Bayley Scales of Infant and Toddler Development, Third Edition (cognitive, fine, and gross motor scores) at 24 months corrected age (n = 112), Griffiths Mental Development Scales (developmental quotient) at age 3.5 years (n = 98), Movement Assessment Battery for Children, Second Edition (n = 85), and Wechsler Preschool and Primary Scale of Intelligence, Third Edition at age 5.5 years (n = 44). Corrections were made for intracranial volume, maternal education, and severe brain lesions. Ventricular volumes were negatively related to neurodevelopmental outcome at age 24 months and 3.5 years, as well as processing speed at age 5.5 years. Unmyelinated white matter (UWM) volume was positively associated with motor outcome at 24 months and with processing speed at age 5.5 years. Cortic...Continue Reading

References

Sep 6, 2000·Medical Image Analysis·S K WarfieldR Kikinis
Feb 3, 2005·Pediatrics·Terrie E InderJoseph J Volpe
Aug 18, 2006·The New England Journal of Medicine·Lianne J WoodwardTerrie E Inder
Jan 4, 2008·European Journal of Pediatrics·Agnes MesserschmidtRobert Birnbacher
Sep 19, 2008·Brain : a Journal of Neurology·Miriam H BeauchampPeter J Anderson
Oct 7, 2008·Biological Psychiatry·John H GilmoreGuido Gerig
Oct 16, 2009·Archives of Disease in Childhood·G RobertsUNKNOWN Victorian Infant Collaborative Study Group
Apr 7, 2010·Archives of Pediatrics & Adolescent Medicine·Peter J AndersonUNKNOWN Victorian Infant Collaborative Group
Oct 15, 2011·AJNR. American Journal of Neuroradiology·B J M van KooijS J Counsell
Jan 4, 2012·Developmental Medicine and Child Neurology·Britt J M Van KooijFloris Groenendaal
Jan 31, 2012·Developmental Medicine and Child Neurology·Jorrit F de KievietJaap Oosterlaan
Feb 22, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·K KeunenM J N L Benders
Mar 20, 2013·Cerebral Cortex·Vanessa KyriakopoulouMary Rutherford
Apr 27, 2013·AJNR. American Journal of Neuroradiology·H KidokoroT E Inder
May 9, 2013·The Cerebellum·Sylke J SteggerdaGerda van Wezel-Meijler
Aug 13, 2013·Frontiers in Human Neuroscience·Miloš JudašIvica Kostović
Dec 21, 2013·PloS One·Petronella AnbeekManon J N L Benders
Jan 21, 2014·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Samudragupta BoraLianne J Woodward
Feb 4, 2014·Cerebral Cortex·Nelly PadillaUlrika Adén
Feb 18, 2014·The Journal of Pediatrics·Béatrice SkiöldUlrika Adén
Mar 13, 2014·Annals of Neurology·Stephen A Back, Steven P Miller
Nov 18, 2014·BMC Pediatrics·Lex W DoyleLianne J Woodward

❮ Previous
Next ❯

Citations

Apr 14, 2016·Pediatric Research·Sirkku SetänenLeena Haataja
Oct 27, 2016·Acta Paediatrica·Isabel Benavente-FernandezUNKNOWN Neonatal Neurology Foundation (Fundación Nene)
Jul 5, 2017·Developmental Medicine and Child Neurology·Kristin KeunenMartijn P van den Heuvel
Jan 20, 2018·Developmental Medicine and Child Neurology·Aurelie PascalChristine Van den Broeck
Nov 15, 2018·CoDAS·Amanda Tragueta Ferreira-Vasques, Dionísia Aparecida Cusin Lamônica
Sep 13, 2017·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Lotte G van den HeuijLaura Bennet
Aug 3, 2018·Development and Psychopathology·Moriah E ThomasonRoberto Romero
Feb 17, 2018·Nature Reviews. Neuroscience·John H GilmoreWei Gao
Aug 31, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Marcus LoSandrine de Ribaupierre
Sep 30, 2019·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Chandler Rebecca Lee MongersonDusica Bajic
May 28, 2020·Plastic and Reconstructive Surgery·Liyun TuMarius George Linguraru
Feb 9, 2018·Cerebral Cortex·Shaili C JhaRebecca C Knickmeyer
Aug 21, 2019·Frontiers in Pediatrics·Chandler R L MongersonDusica Bajic
May 26, 2017·Developmental Medicine and Child Neurology·Nathalie H P ClaessensManon J N L Benders
Sep 1, 2018·Journal of Perinatology : Official Journal of the California Perinatal Association·Rebecca A DornerBruno P Soares
Mar 7, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Maria Cristina AisaBenito Cappuccini
Feb 8, 2021·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·André M Graça, Frances M Cowan
May 26, 2021·Pediatric Research·Charlotte van 't WestendeCacha M P C D Peeters-Scholte
May 18, 2021·Ultrasound in Medicine & Biology·Maria Cristina AisaGian Carlo Di Renzo
Jul 16, 2021·Archives of Disease in Childhood. Fetal and Neonatal Edition·Thiviya SelvanathanSteven P Miller
Aug 16, 2021·Pediatric Research·Lisa M HortensiusManon J N L Benders
Aug 21, 2021·Developmental Medicine and Child Neurology·Raymond StegemanUNKNOWN CHD LifeSpan Study Group Utrecht
Sep 12, 2021·Pediatric Research·Mercedes I BeltránAgnes van den Hoogen
Jan 14, 2018·Pediatrics·Julia GunkelJoppe Nijman
Feb 15, 2018·Pediatrics·Juliane SchneiderSteven P Miller

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis