Brainstem auditory-evoked potentials studied with paired stimuli in multiple sclerosis patients

European Neurology
J ZeitlhoferH P Ludin

Abstract

In 19 patients with definite multiple sclerosis (MS) brainstem auditory-evoked potentials (BAEP) with paired stimuli were recorded. Only hearing pathways without abnormalities in usual BAEP were examined. The latencies of wave III and wave V were significantly increased with the paired-stimulus technique (using paired-click intervals of 1.5 and 4.0 ms duration) compared to single clicks. In 4 patients (21%) paired-click BAEP latencies exceeded the critical values of normal subjects. This technique might give new possibilities in detecting minor lesions in MS patients.

Citations

Mar 29, 1996·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·P Anand
Apr 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·E KuneschH J Freund

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