BrainTrap: a database of 3D protein expression patterns in the Drosophila brain.

Database : the Journal of Biological Databases and Curation
Seymour Knowles-BarleyJ Douglas Armstrong

Abstract

Protein-trap strains of Drosophila melanogaster provide a very useful tool for examining the 3D-expression patterns of proteins and purification of protein complexes. Here we present BrainTrap, available at http://fruitfly.inf.ed.ac.uk/braintrap, an online database of 3D confocal datasets showing reporter gene expression and protein localization in the adult brain of Drosophila. Full size images throughout the volume of the entire brain can be viewed interactively in a web browser. The database includes searchable annotations linked to the FlyBase Drosophila anatomy ontology. Anatomical search criteria can be specified using automatic completion and a hierarchical browser for the ontology. The provenance of all annotation is retained and the location where the annotator made the conclusion can be highlighted. Database URL: http://fruitfly.inf.ed.ac.uk/braintrap.

References

Jul 26, 2000·The Journal of Cell Biology·M E FortiniI K Hariharan
Dec 14, 2001·Proceedings of the National Academy of Sciences of the United States of America·X MorinW Chia
Jan 17, 2002·Functional & Integrative Genomics·M YoshiharaJ T Littleton
Jul 9, 2004·Briefings in Functional Genomics & Proteomics·Edward Ryder, Steven Russell
Apr 13, 2005·Current Biology : CB·Shouzhen XiaAnn-Shyn Chiang
Jul 19, 2005·Annual Review of Neuroscience·Ronald L Davis
Dec 31, 2005·Nucleic Acids Research·Gary Grumbling, Victor Strelets
Jun 6, 2006·Gene Expression Patterns : GEP·Dieter MaierAnette Preiss
Jun 8, 2006·Annual Review of Genomics and Human Genetics·Trudy F C Mackay, Robert R H Anholt
Jun 10, 2008·Nature Neuroscience·Richard D EmesSeth G N Grant

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Citations

Nov 12, 2013·Nature Cell Biology·Ruei-Jiun HungJonathan R Terman
May 3, 2011·Nature Methods·Hanchuan PengJulie H Simpson
Sep 2, 2011·Physical Chemistry Chemical Physics : PCCP·Eric L FirstChristodoulos A Floudas
Dec 20, 2011·Bioinformatics·Nestor MilyaevJ Douglas Armstrong
Feb 1, 2008·BMC Bioinformatics·Violaine MoreauFranck Molina
Aug 13, 2013·PloS One·Jürgen DönitzGregor Bucher
Dec 19, 2013·PloS One·Helen L FitzsimonsMaxwell J Scott
Nov 16, 2017·Proceedings of the National Academy of Sciences of the United States of America·L D Ríos-BarreraM Leptin
May 29, 2020·Journal of Integrative Bioinformatics·Irene MartorelliFons J Verbeek
Aug 11, 2020·Journal of Paediatrics and Child Health·Alice MonzaniPier Luigi Ingrassia
Mar 27, 2020·Frontiers in Physiology·Renata Van De Maas de AzevedoCharalambos P Kyriacou
Jun 6, 2017·Nature Methods·Xi LongTimothée Lionnet
May 14, 2021·Science Advances·Shannon K RichJonathan R Terman

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Methods Mentioned

BETA
protein-trap
Protein Trap
imaging techniques
protein

Software Mentioned

BrainTrap

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