BrainWiki-A Wiki-Style, User Driven, Comparative Brain Anatomy Tool

Frontiers in Neuroanatomy
Linda ForsellS Abid Hussaini

Abstract

The mouse is the most important animal model within neuroscientific research, a position strengthened by the wide-spread use of transgenic mouse models. Discoveries in animals are followed by corroboration in humans, and the interchange between these fields of research is essential to our understanding of the human brain. With the advent of advanced technologies such as single-cell transcriptomics, epigenetic profiling and diffusion MRI, many prominent research institutes and collaborations have emerged, aiming to construct complete human or mouse brain atlases with data on gene expression, connectivity and cell types. These initiatives are indispensable resources, but frequently require extensive, time-consuming development, and rely on updates by the provider. They often come in the shape of applications which require practice or prior technical know-how. Importantly, none of them place the human and the mouse brain next to each other to allow for immediate comparison. We present BrainWiki, a user-friendly, web-based atlas that links the human and the mouse brain together, side-by-side. The platform gives the user a simple overview of brain anatomy along with published articles relating to each brain region that allows the us...Continue Reading

References

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Methods Mentioned

BETA
transgenic
imaging techniques

Software Mentioned

Brainnetome
Disqus API
BrainWiki
PubMed
SVG
Workbench
Allen Brain Atlas
Allen Atlas
Whole Brain
Disqus

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