Breast arterial calcification is associated with reproductive factors in asymptomatic postmenopausal women.

Journal of Women's Health
Lawrence F BielakPatricia A Peyser

Abstract

The etiology of breast arterial calcification (BAC) is not well understood. We examined reproductive history and cardiovascular disease (CVD) risk factor associations with the presence of detectable BAC in asymptomatic postmenopausal women. Reproductive history and CVD risk factors were obtained in 240 asymptomatic postmenopausal women from a community-based research study who had a screening mammogram within 2 years of their participation in the study. The mammograms were reviewed for the presence of detectable BAC. Age-adjusted logistic regression models were fit to assess the association between each risk factor and the presence of BAC. Multiple variable logistic regression models were used to identify the most parsimonious model for the presence of BAC. The prevalence of BAC increased with increased age (p < 0.0001). The most parsimonious logistic regression model for BAC presence included age at time of examination, increased parity (p = 0.01), earlier age at first birth (p = 0.002), weight, and an age-by-weight interaction term (p = 0.004). Older women with a smaller body size had a higher probability of having BAC than women of the same age with a larger body size. The presence or absence of BAC at mammography may provid...Continue Reading

References

May 1, 1987·The British Journal of Radiology·S J Leinster, G H Whitehouse
Oct 27, 1999·Epidemiology·G S CooperM Bohlig
Jul 10, 2002·Current Opinion in Nephrology and Hypertension·Linda L DemerFarhad Parhami
Feb 13, 2004·Mayo Clinic Proceedings·Terence M DohertyRobert C Detrano
Feb 26, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·William G GoodmanUNKNOWN Vascular Calcification Work Group
Apr 7, 2004·Fertility and Sterility·UNKNOWN Practice Committee of the American Society for Reproductive Medicine
Apr 15, 2004·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Michael BaileyNarendra Vyavahare
Jun 10, 2004·Journal of Women's Health·Carlos IribarrenDavid B Spring
Sep 8, 2004·Maturitas·Jose Russo, Irma H Russo
Apr 21, 2005·Annals of Epidemiology·Jhansi ReddyLori Mosca
Dec 31, 2005·Social Biology·Yang Yang, S Philip Morgan
May 27, 2006·Endocrine-related Cancer·A M Lorincz, S Sukumar
Jul 13, 2006·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Jose RussoIrma H Russo
Nov 23, 2006·The Journal of Steroid Biochemistry and Molecular Biology·J Russo, Irma H Russo
Mar 9, 2007·European Journal of Radiology·Ugur TopalAli Aydinlar
Jan 18, 2008·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Jose RussoIrma H Russo

❮ Previous
Next ❯

Citations

Sep 20, 2020·International Journal of Cancer. Journal International Du Cancer·Shadi AzamPer Hall
Apr 22, 2017·Radiologia brasileira·Flávio Augusto Teixeira RonzaniNatália Maria da Silva Fernandes

❮ Previous
Next ❯

Methods Mentioned

BETA
Coronary Artery Calcification

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.